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PeerView Heart, Lung & Blood CME/CNE/CPE Audio Podcast - Mollie Moran, APRN-CNP, AOCNP - Taking Aim at B-Cell Malignancies With BTK Inhibitors: Oncology Nurse Perspectives and Insights on Clinical Care

Mollie Moran, APRN-CNP, AOCNP - Taking Aim at B-Cell Malignancies With BTK Inhibitors: Oncology Nurse Perspectives and Insights on Clinical Care

05/27/19 • 58 min

PeerView Heart, Lung & Blood CME/CNE/CPE Audio Podcast
Go online to PeerView.com/XAC860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, based on a recent live symposium held during the Oncology Nursing Society’s (ONS) 44th Annual Congress, a panel of expert nurse faculty use a MasterClass/case-forum design to offer an in-depth review of BTK inhibitors, their therapeutic applications in B-cell malignancies, and the core nurse-focused practice issues that are central to the further integration of BTK inhibitors into treatment plans for patients with cancers such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), among other B-cell disorders. Upon completion of this activity, participants will be able to: Summarize updated safety and efficacy evidence about first- and second-generation BTK inhibitors in the management of B-cell cancer, Cite dosing considerations, administration strategies, and treatment schedules of BTK inhibitors for the management of newly diagnosed or refractory/relapsed B-cell cancer, Educate patients about the varying side effect profiles, efficacy outcomes, and potential for treatment resistance associated with the use of BTK inhibitors for B-cell cancer, Manage side effect and adherence considerations in patients with B-cell cancer treated with BTK inhibitors.
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Go online to PeerView.com/XAC860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, based on a recent live symposium held during the Oncology Nursing Society’s (ONS) 44th Annual Congress, a panel of expert nurse faculty use a MasterClass/case-forum design to offer an in-depth review of BTK inhibitors, their therapeutic applications in B-cell malignancies, and the core nurse-focused practice issues that are central to the further integration of BTK inhibitors into treatment plans for patients with cancers such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), among other B-cell disorders. Upon completion of this activity, participants will be able to: Summarize updated safety and efficacy evidence about first- and second-generation BTK inhibitors in the management of B-cell cancer, Cite dosing considerations, administration strategies, and treatment schedules of BTK inhibitors for the management of newly diagnosed or refractory/relapsed B-cell cancer, Educate patients about the varying side effect profiles, efficacy outcomes, and potential for treatment resistance associated with the use of BTK inhibitors for B-cell cancer, Manage side effect and adherence considerations in patients with B-cell cancer treated with BTK inhibitors.

Previous Episode

undefined - John C. Byrd, MD - BTK Inhibition as an Anti-Cancer Strategy: Exploring a Model for Modern Targeted Therapy in Hematologic Malignancies and Beyond

John C. Byrd, MD - BTK Inhibition as an Anti-Cancer Strategy: Exploring a Model for Modern Targeted Therapy in Hematologic Malignancies and Beyond

Go online to PeerView.com/EQY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. This PeerView CME/CNE-certified activity—based on a live event conducted in a MasterClass format held in conjunction with the 2019 meeting of the AACR—discusses how Bruton tyrosine kinase (BTK) inhibitors effectively target aspects of B-cell receptor signaling and covers key evidence and clinical issues related to the use of BTK inhibitors in hematologic malignancies (including agent selection, potential combination regimens, and strategies for overcoming drug intolerance or resistance). The panel of experts uses a mix of hard science and practical insight to offer learners an in-depth look at how the BTK inhibitor experience became a model for the development of targeted therapies in cancer, while also exploring the future applications of this unique drug class. Upon completion of this activity, participants will be able to: Cite the biologic rationale and anti-cancer mechanisms of BTK inhibition, Summarize updated evidence on the safety and efficacy of first- and second-generation BTK inhibitors in the management of B-cell cancers, Integrate BTK inhibitor–based strategies into the management of patients with B-cell malignancies, including chronic lymphocytic leukemia and mantle cell lymphoma, Manage safety considerations in patients with B-cell malignancies who are receiving therapy with BTK inhibitors.

Next Episode

undefined - Leora Horn, MD, MSc, FRCPC - The Present and Future of Immunotherapy as a Key Component of the Treatment Arsenal for Locally Advanced & Earlier Stages of Lung Cancer

Leora Horn, MD, MSc, FRCPC - The Present and Future of Immunotherapy as a Key Component of the Treatment Arsenal for Locally Advanced & Earlier Stages of Lung Cancer

Go online to PeerView.com/DHV860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Immune checkpoint inhibitor therapy is the new standard of care for patients with stage III, unresectable NSCLC who have not had disease progression after concurrent chemoradiotherapy. Immunotherapy-based treatment approaches are also being explored in multiple clinical trials in neoadjuvant and adjuvant settings in earlier stages of lung cancer. What is the rationale for and the evidence supporting the use of immunotherapy in locally advanced and early-stage lung cancer? How can we optimally integrate checkpoint inhibitors in the context of multimodal therapy? What factors and nuances should be taken into account when using immunotherapy in the management of patients with stage III NSCLC? In this activity, based on a recent live symposium held in San Diego, California, a panel of experts discusses the answers to these questions in the context of the latest evidence and provides practical guidance on how to transition immunotherapy into earlier stages of lung cancer in this MasterClass and Practicum. Upon completion of this activity, participants will be able to: Discuss the rationale for use, mechanisms of action, and role of immunotherapy in the management of lung cancer, Assess the latest data on the efficacy and safety of immunotherapy in stage III NSCLC, and the clinical implications of these data, Describe key trials assessing immune-based treatment approaches in locally advanced or earlier stages of lung cancer, Incorporate immunotherapy into treatment plans for patients with locally advanced or earlier stages of lung cancer, including in the context of clinical practice or clinical trials, based on the latest evidence, recommendations, and effective multidisciplinary collaboration and co-ordination of care.

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