
New Challenges from an Ancient Disease – Drug-Resistant Tuberculosis
04/18/23 • 14 min
Consumption. The White Plague. Scrofula. Tuberculosis (TB) has been known by so many names over the ages, and those names reflect just how long it’s been around and just how misunderstood it’s been. It’s killed kings and generals, playwrights, and poets.
TB still sickens 10 million people every year and kills 1.5 million – even though it’s easily prevented and can be treated. It’s unusual because it needs to be treated even if the person infected has no symptoms at all.
And even though it’s an ancient disease, TB keeps evolving into new and ever more unpleasant forms. Now, multi-drug-resistant (MDR) TB infects half a million people around the world each year, according to the World Health Organization. A third of these MDR TB infections go undetected, and that means there are tens of millions of people who do not get the treatment they need and who can go on to infect others.
Dr. Jeffrey Tornheim has been studying ways to test people to quickly and easily tell if they’ve got a drug-resistant form of TB infection and need special medications to treat it right away. Quick information can help stop the spread of these dangerous forms of the infection and can ensure that patients and health professionals don’t waste time, money, and medicine with the wrong treatments.
In this episode of One World One Health, Dr. Tornheim, Assistant Professor of Medicine and Assistant Professor of Pediatrics at the Johns Hopkins University School of Medicine, as well as at the Johns Hopkins Bloomberg School of Public Health, chats with host Maggie Fox about why TB is so hard to fight and how genomics can make that fight a little easier.
Consumption. The White Plague. Scrofula. Tuberculosis (TB) has been known by so many names over the ages, and those names reflect just how long it’s been around and just how misunderstood it’s been. It’s killed kings and generals, playwrights, and poets.
TB still sickens 10 million people every year and kills 1.5 million – even though it’s easily prevented and can be treated. It’s unusual because it needs to be treated even if the person infected has no symptoms at all.
And even though it’s an ancient disease, TB keeps evolving into new and ever more unpleasant forms. Now, multi-drug-resistant (MDR) TB infects half a million people around the world each year, according to the World Health Organization. A third of these MDR TB infections go undetected, and that means there are tens of millions of people who do not get the treatment they need and who can go on to infect others.
Dr. Jeffrey Tornheim has been studying ways to test people to quickly and easily tell if they’ve got a drug-resistant form of TB infection and need special medications to treat it right away. Quick information can help stop the spread of these dangerous forms of the infection and can ensure that patients and health professionals don’t waste time, money, and medicine with the wrong treatments.
In this episode of One World One Health, Dr. Tornheim, Assistant Professor of Medicine and Assistant Professor of Pediatrics at the Johns Hopkins University School of Medicine, as well as at the Johns Hopkins Bloomberg School of Public Health, chats with host Maggie Fox about why TB is so hard to fight and how genomics can make that fight a little easier.
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Making Superbugs Visible – Filming AMR
Antimicrobial resistance – the emergence of new drug-resistant superbugs – is one of the top 10 global health threats, the World Health Organization says.
More than 700,000 people die each year from infections caused by drug-resistant microorganisms – which not only include antibiotic-resistant bacteria but also viruses, fungi, and parasites that can escape the effects of drugs designed to kill them.
Filmmaker Michael Wech illustrates the problem with a series of stories about real people in his documentary “The Silent Pandemic”.
In this episode of One World, One Health, listen as Michael explains why he’s so deeply interested in the danger of antimicrobial resistance and what he has found out about efforts to curb it.
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Tick, Tick... Boom! – Climate Change, tick tracking, and One Health
A walk in the woods can bring serenity and peace of mind. You can bring back souvenirs such as a beautiful leaf, or a pine cone. Sometimes your souvenir is less lovely - a tick. Dogs, cats, and even horses can suffer from tick bites and responsible pet owners regularly check their companions for these unwelcome parasites.
Ticks can carry and transmit bacteria, viruses, and parasites that cause Lyme disease, anaplasmosis, Powassan virus, babesiosis, and erlichiosis.
Climate change is making new regions more tick-friendly, which is bad news for people and animals.
Dr. Katie Clow is an Assistant Professor in One Health in the Department of Population Medicine at the Ontario Veterinary College at Canada’s University of Guelph. She’s working on better ways to track ticks and their spread. She’s also got a website with useful information about ticks for people and pet owners.
In this episode of One World, One Health, listen as Katie explains why people need to keep an eye out for ticks, why simply clearing wildlife such as deer won’t help control ticks, and how climate change is helping ticks thrive in more regions of the world.
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