Normal Curves: Sexy Science, Serious Statistics
Regina Nuzzo and Kristin Sainani
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Sugar Sag: Is Your Diet Aging You?
Normal Curves: Sexy Science, Serious Statistics
05/19/25 • 68 min
Wrinkles and sagging skin—just normal aging, or can you blame your sweet tooth? We dive into “sugar sag,” exploring how sugar, processed foods, and even your crispy breakfast toast might be making you look older than if you’d said no to chocolate cake and yes to broccoli. Along the way, we encounter statistical adjustment, training and test data sets, what we call “references to nowhere,” plus some cadavers and collagen. Ever heard of an AGE reader? Find out how this tool might offer a sneak peek at your date’s age—and maybe even a clue about his... um... “performance.”
Statistical topics
- Training and test sets
- Statistical adjustment
- Overfitting
- Plagiarism
- Proper citing practices
- References to nowhere
Methodologic morals
- “When you plagiarize, you steal the errors too.”
- “Overdone statistical adjustment is like overdone photo filters–at a certain point it’s just laughable.”
Citations
Collagen turnover:
- Verzijl N, DeGroot J, Thorpe SR, et al.Effect of Collagen Turnover on the Accumulation of Advanced Glycation End Products. JBC. 2000;275:39027-31.
Cadaver study:
- Hamlin CR, Kohn RR, Luschin JH. Apparent Accelerated Aging of Human Collagen in Diabetes Mellitus. Diabetes. 1975; 24: 902–904.
Studies of AGEs and diabetes and health:
- Monnier VM, Cerami A. Nonenzymatic browning in vivo: possible process for aging of long-lived proteins. Science. 1981;211:491-3.
- Brownlee M, Vlassara H, Cerami A. Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann Intern Med. 1984;101:527-37.
- Monnier VM, Vishwanath V, Frank KE, et al. Relation between Complications of Type I Diabetes Mellitus and Collagen-Linked Fluorescence. N Engl J Med. 1986;314:403-408.
- Monnier VM, Sell DR, Abdul-Karim FW, et al. Collagen browning and cross-linking are increased in chronic experimental hyperglycemia. Relevance to diabetes and aging. Diabetes. 1988;37:867-72.
- Monnier VM, Bautista O, Kenny D, et al. Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. Diabetes 1999; 48: 870–80.
- Genuth S, Sun W, Cleary P, et al. Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes. Diabetes. 2005;54:3103-11.
- van Waateringe RP, Slagter SN, van Beek AP, et al. Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is associated with the metabolic syndrome and its individual components. Diabetol Metab Syndr. 2017;9:42.
- Kouidrat Y, Zaitouni A, Amad A, et al. Skin autofluorescence (a marker for advanced glycation end products) and erectile dysfunction in diabetes. J Diabetes Complications. 2017;3:108-113.
- Fujita N, Ishida M, Iwane T, et al. Association between Advanced Glycation End-Products, Carotenoids, and Severe Erectile Dysfunction. World J Mens Health. 2023;41:701-11.
- Uruska A, Gandecka A, Araszkiewicz A, et al. Accumulation of advanced glycation end products in the skin is accelerated in relation to insulin resistance in people with Type 1 diabetes mellitus. Diabet Med. 2019;36:620-625.
- Boersma HE, Smit AJ, Paterson AD, et al.
1 Listener
Alcohol: Are happy hours good for your heart?
Normal Curves: Sexy Science, Serious Statistics
04/21/25 • 65 min
Does a daily glass of wine really keep the cardiologist away? It’s a claim we’ve all heard: light to moderate drinking is good for your heart. But is it science or just a convenient excuse for happy hour? In this episode, we dive into the history behind this claim, discuss the challenges of observational studies and statistical adjustment, and explore attempts at randomized trials and natural experiments to get to the bottom of this boozy debate. Grab your drink—or maybe don’t—and join us!
Statistical topics
- Statistical Adjustment
- Regression
- Residual and Unmeasured Confounding
- Randomized Trials
- Multiple Testing
- Outcome Switching
- Mendelian Randomization
Methodological morals
“Statistical adjustment cannot erase all confounding.”
“When you can’t experiment on people, let Nature experiment on people.”
Citations
- Alcohol and Drinking. Gallup Poll. 2024.
- Canada’s Guidance on Alcohol and Health. Canadian Centre on Substance Use and Addiction. 2023.
- U.S. Department of Agriculture and U.S. Department of Health and Human Services. 2020 – 2025 Dietary Guidelines for Americans. 2020.
- U.S. Department of Agriculture and U.S. Department of Health and Human Services. Alcohol and Cancer Risk: The US Surgeon General's Advisory. 2025.
- Mezue K, Osborne MT, Abohashem S, et al. Reduced stress-related neural network activity mediates the effect of alcohol on cardiovascular risk. JACC. 2023;81:2315-25.
- McPhillips D, Goodman B. Small amounts of alcohol may turn down stress in the brain, benefiting the heart, new study finds. CNN. June 12, 2023.
- Friedman GD, Klatsky AL. Is alcohol good for your health? NEJM. 1993;329:1882-3.
- Sainani K. Alcohol and Weight. Allure. July 14, 2010.
- Wang LU, Lee IM, Manson JE, et al. Alcohol consumption, weight gain, and risk of becoming overweight in middle-aged and older women. Arch Intern Med. 2010;170:453-61.
- Sainani K. Drinking and Weight. Allure. Oct 31, 2008.
- Tolstrup JS, Halkjær J, Heitmann BL, et al. Alcohol drinking frequency in relation to subsequent changes in waist circumference. Am J Clin Nutr. 2008;87:957-63.
- Rabin RC. Major Study on Drinking Will be Shut Down. New York Times. June 15, 2018.
- Mitchell G, Lesch M, McCambridge J. Alcohol industry involvement in the moderate alcohol and cardiovascular health trial. AJPH. 2020;110:485-8.
- Gepner Y, Golan R, Harman-Boehm I, et al. Effects of Initiating Moderate Alcohol Intake on Cardiometabolic Risk in Adults With Type 2 Diabetes: A 2-Year Randomized, Controlled Trial. Ann Intern Med. 2015;163:569-79.
- Slade E, Drysdale H, Goldacre B, et al. Discrepancies between prespecified and reported outcomes. Ann Intern Med. 2016;164:374.
- Biddinger KJ, Emdin CA, Haas ME, et al. Association of habitual alcohol intake with risk of cardiovascular disease. JAMA Netw Open. 2022;5:e223849.
Page with more details on the CASCADE trial
Kristin and Regina’s online courses:
The Red Dress Effect: Are women in red sexier?
Normal Curves: Sexy Science, Serious Statistics
04/07/25 • 68 min
Wear red and drive men wild with lust – or so says scientific research on color’s role in human mating. But can a simple color swap really boost a woman’s hotness score? In this episode, we delve into the evidence behind the Red Dress Effect, from a controversial first study in college men to what the latest research says about who this trick might work for (and who it might not). Along the way we encounter red monkey butts, old-Internet websites, the Winner’s Curse in scientific research, adversarial collaborations, and why size (ahem, sample size) really does matter.
Statistical topics
- Reproducibility crisis in psychology
- Sample size
- Selection bias
- Winner’s curse
- Cohen’s d standardized effect size
- Adversarial collaboration
- Meta-analysis
- Preregistration
- Publication bias
- Statistical moderators
Methodological morals
“The smaller the sample, the flashier the result, the less you should trust it.”
“Good scientists learn from their statistical mistakes and fix them.”
References
- Clarke, G. How to Be Sexy: 7 Weird (But True) Rules of Attraction. Allure. January 23, 2013.
- Nuzzo, R. Vying for a soul mate? Psych out the competition with science. Los Angeles Times. December 8, 2008.
- Vying for a Soul Mate on the Today Show, December 30, 2008.
- Elliot, A.J. and Niesta, D. Romantic red: red enhances men's attraction to women. Journal of personality and social psychology. 2008; 95: 1150 – 1164.
- Lehrer, J. The Truth Wears Off. The New Yorker , December 5, 2010.
- MacMahon, B., Yen, S., Trichopoulos, D., Warren, K. and Nardi, G. Coffee and cancer of the pancreas. New England Journal of Medicine. 1981; 304: 630-633.
- Ioannidis, J.P. Why most published research findings are false. PLoS medicine. 2005; 2(8), e124
- Lehmann, G.K., Elliot, A.J. and Calin-Jageman, R.J. Meta-analysis of the effect of red on perceived attractiveness. Evolutionary Psychology. 2018; 16: 1474704918802412.
- Pazda, A.D., Thorstenson, C.A. and Elliot, A.J. The effect of red on attractiveness for highly attractive women. Curr Psychol. 2023; 42: 8066–8073
Kristin and Regina’s online courses:
Demystifying Data: A Modern Approach to Statistical Understanding
Clinical Trials: Design, Strategy, and Analysis
Medical Statistics Certificate Program
Epidemiology and Clinical Research Graduate Certificate Program
Chapters
- (00:00) - Introduction
- (06:04) - Red Dress Effect on TV
- (10:01) - Red Monkey Butts
- (12:56) - 2008 Study on Romantic Red
- (16:04) - HotOrNot.com
- (20:10) - 2008 Study Results
- (25:10) - Cohen’s d Standardized Effect Size
- (30:52) - Problems with Small Sample Sizes
- (34:12) - Winner’s Curse and Publication Bias
- (38:40) - Reproducibility Crisis
- (44:03) - Adversarial Collaboration
- (49:01) - Meta-Analysis and Pre-Registration
- (55:23) - Adversarial Discussion Sections and Updates
- (01:02:55) - Latest Red Study
- (01:06:26) - Wrap-Up
Normal Curves Trailer
Normal Curves: Sexy Science, Serious Statistics
02/13/25 • 2 min
Normal Curves is a podcast about sexy science & serious statistics. Ever try to make sense of a scientific study and the numbers behind it? Listen in to a lively conversation between two stats-savvy friends who break it all down with humor and clarity. Professors Regina Nuzzo of Gallaudet University and Kristin Sainani of Stanford University discuss academic papers journal club-style — except with more fun, less jargon, and some irreverent, PG-13 content sprinkled in. Join Kristin and Regina as they dissect the data, challenge the claims, and arm you with tools to assess scientific studies on your own.
Pheromones: Is sexy sweat the key to genetic diversity?
Normal Curves: Sexy Science, Serious Statistics
02/24/25 • 57 min
Sweaty t-shirt dating parties, sex pheromone dating sites, choosing your dating partner by sniffing them up — wacko fringe fads or evidence-based mating strategies? And what does your armpit stain have to do with your kids’ immune systems, or hormonal contraceptive pills, or divorce rates?
In this episode of Normal Curves, Kristin and Regina reach back into the 1990s and revisit the scientific paper that started it all: The Sweaty T-Shirt Study. They bring a sharp eye and open mind, critically examining the study and following the line of research to today. Along the way, they encounter interesting statistical topics—including correlated observations, within-person study design, and bar-chart blasphemy—with a short, surprising detour into Neanderthal sex.
Statistical topics
- Correlated observations
- Within-person study design
- Bar charts
- Data and methodological transparency
- Cherry-picking
- Meta-analysis
- Multiple testing
- Post-hoc analyses
Methodological morals
“Repeat after me: Bar charts are not for numerical data.”
“Those who ignore dependencies in their data are destined for flawed conclusions.”
References
- Nuzzo, R. Ah, Love at first whiff. Los Angeles Times. May 19, 2008.
- Papamarko, S. Pheromone parties attempt to match singles by scent. Yahoo!life. April 12, 2012.
- Sainani, K. Stone Age Gene Swap. Stanford Magazine. November/December 2011.
- Aldhous, P. Darling, You Smell Wonderfully Different. New Scientist. 6 May 1995.
- Wedekind C, Seebeck T, Bettens F, Paepke AJ. MHC-dependent mate preferences in humans. Proc Biol Sci. 1995; 260(1359):245-249. doi:10.1098/rspb.1995.0087
- Hedrick P, Loeschcke V. MHC and mate selection in humans?. Trends Ecol Evol. 1996;11(1):24. doi:10.1016/0169-5347(96)80237-0
- Wedekind C, Seebeck T. Reply from C. Wedekind and T. Seebeck. Trends Ecol Evol. 1996;11(1):24-25. doi:10.1016/0169-5347(96)81061-5
- Wedekind C, Füri S. Body odour preferences in men and women: do they aim for specific MHC combinations or simply heterozygosity?. Proc Biol Sci. 1997;264(1387):1471-1479. doi:10.1098/rspb.1997.0204
- Havlíček J, Winternitz J, Roberts SC. Major histocompatibility complex-associated odour preferences and human mate choice: near and far horizons. Philos Trans R Soc Lond B Biol Sci. 2020;375(1800):20190260. doi:10.1098/rstb.2019.0260
Kristin and Regina’s online courses:
Demystifying Data: A Modern Approach to Statistical Understanding
Clinical Trials: Design, Strategy, and Analysis
Medical Statistics Certificate Program
Epidemiology and Clinical Research Graduate Certificate Program
Programs that we teach in:
Epidemiology and Clinical Research Graduate Certificate Program
Find us on:
Kristin -
Vitamin D Part 2: Good for more than just your bones?
Normal Curves: Sexy Science, Serious Statistics
03/24/25 • 69 min
Can you really sit on your couch, pop vitamin D pills, and shave seconds off your 5k? Touted as a miracle cure-all, vitamin D is claimed to slash cancer and infection risks while boosting mood, cognition, and athletic performance. But does upping your vitamin D really make you healthier and happier? In this episode, we’ll follow the epidemiologic evidence—from clues in petri dishes through randomized trials. Along our journey, we’ll encounter chocolate-fueled Nobel Prizes, rock stars, pasty Brits, and a tangled mess of promiscuous variables.
Statistical topics
- ecological studies
- ecological fallacy
- correlation is not causation
- observational studies
- statistical adjustment
- confounding
- randomized trials
- factorial design
- post-hoc analyses
- subgroup analyses
Methodologic morals
- “Variables with too many entanglements make observational studies a fool’s game.”
- “If your intervention works only when you torture your data, it’s probably a false confession.”
Citations
Garland CF, Garland FC. Do sunlight and vitamin D reduce the likelihood of colon cancer? Int J Epidemiol. 1980;9:227-31.
Messerli FH. Chocolate consumption, cognitive function, and Nobel laureates. N Engl J Med. 2012;367:1562-64.
Holick, MF. The Vitamin D Solution: A 3-Step Strategy to Cure Our Most Common Health Problems. Penguin Publishing Group, 2011.
McMillan A. Can vitamin D boost your fitness routine? Dec 18, 2018.
Marawan A, Kurbanova N, Qayyum R. Association between serum vitamin D levels and cardiorespiratory fitness in the adult population of the USA. Eur J Prev Cardiol. 2019;26:750-55.
Vitamin D levels in the blood linked to cardiorespiratory fitness. European Society of Cardiology. Oct 30, 2018.
Jones AM, Kirby BS, Clark IE, et al. Physiological demands of running at 2-hour marathon race pace. J Appl Physiol. 2021;130:369-79.
Manson JE, Bassuk SS, Lee IM, et al. The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease. Contemp Clin Trials. 2012;33:159-71.
Manson JE, Cook NR, Lee IM, et al. Vitamin D supplements and prevention of cancer and cardiovascular disease. NEJM. 2019;380:33-44.
Lee KL, McNeer JF, Starmer CF, et al. Clinical judgment and statistics: lessons from a simulated randomized trial in coronary artery disease. Circulation. 1980; 61:508-15.
Wood S. VITAL: No Benefits to Vitamin D and Omega-3s in Reducing Major CV Events, Cancer. TCTMD.com. Nov 10, 2018.
Neale RE, Baxter C, Romero BD, et al. The D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality. Lancet Diabetes Endocrinol. 2022;10:120-28.
Okereke OI, Reynolds CF, Mischoulon D, et al. Effect of Long-term Vitamin D3 Supplementation vs Placebo on Risk of Depression or Clinically Relevant Depressive Symptoms and on Change in Mood Scores: A Randomized Clinical Trial. JAMA. 2020;324:471-80.
LeBoff MS, Murata EM, Cook NR, et al. VITamin D and OmegA-3 TriaL (VITAL): Effects of Vitamin D Supplements on Risk of Falls in the US Population. J Clin Endocrinol Metab. 2020;105:2929-38.
Albert CM, Cook NR, Pester J, et al. Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial. JAMA. 2021;325:1061-73.
Rist PM, Buring JE, Cook NR, et al. Effect of Vitamin ...
Normal Curves: Who are we and what is this podcast about?
Normal Curves: Sexy Science, Serious Statistics
02/17/25 • 13 min
Welcome to a lively conversation about science that's like a journal club, but with less jargon, more fun, and a touch of PG-13 flair. In this introduction, Professors Regina Nuzzo and Kristin Sainani share how they met in graduate school, what they’ve been doing since then, how they’ll choose edgy topics and journal articles to dissect, and a bit about what makes them tick. Join them for their fresh, engaging take on scientific studies, data analysis, and statistical sleuthing.
Kristin and Regina’s online courses:
Demystifying Data: A Modern Approach to Statistical Understanding
Clinical Trials: Design, Strategy, and Analysis
Medical Statistics Certificate Program
Program that we teach in:
Epidemiology and Clinical Research Graduate Certificate Program
Find us on:
Kristin - LinkedIn & Twitter/X
Regina - LinkedIn & ReginaNuzzo.com
- (00:00) - Introduction to Normal Curves
- (03:49) - How We Met and Our Lasting Friendship
- (05:24) - Career Paths
- (08:07) - The Art of Evaluating Scientific Studies
- (09:06) - Personal Health Journeys and Biases
- (10:48) - Shameless Course Plugs & Teaching
- (12:37) - Podcast Origins & Conclusion
Vitamin D Part 1: Is the Deficiency Epidemic Real?
Normal Curves: Sexy Science, Serious Statistics
03/10/25 • 83 min
Is America really facing an epidemic of vitamin D deficiency? While this claim is widely believed, the story behind it is packed with twists, turns, and some pesky statistical cockroaches. In this episode, we’ll dive into a study on Hawaiian surfers, expose how shifting goalposts can create an epidemic, tackle dueling medical guidelines, and flex our statistical sleuthing skills. By the end, you might wonder if the real deficiency lies in the data.
Statistical topics
- dichotomization
- normal distribution
- standard deviation
- researcher biases
- conflicts of interest
- statistical sleuthing
Methodologic morals
- “Arbitrary thresholds make for arbitrary diseases.”
- “Statistical errors are like cockroaches: Where there’s one, there’s many.”
Note that all blood vitamin D levels discussed in the podcast are 25-hydroxyvitamin D levels given in units of ng/ml. To convert from ng/ml to nmol/L, use the formula: nmol/L=2.5*ng/ml. For example, a vitamin D level of 30 ng/mL corresponds to 75 nmol/L.
Citations
Dr. Rhonda Patrick: Micronutrients for Health & Longevity. Huberman Lab Podcast . May 1, 2022
Noh CK, Lee MJ, Kim BK, et al. A Case of Nutritional Osteomalacia in Young Adult Male. J Bone Metab. 2013; 20:51-55.
Binkley N, Novotny R, Krueger D, et al. Low vitamin D status despite abundant sun exposure. J Clin Endocrinol Metab. 2007;92:2130-5.
Malabanan A, Veronikis IE, Holick MF. Redefining Vitamin D Insufficiency. Lancet. 1998;351:805-6.
Dawson-Hughes B, Heaney RP, Holick MF, et al. Estimates of optimal vitamin D status. Osteoporos Int. 2005;16:713-6.
Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266-81.
Cui A, Xiao P, Ma Y, et al. Prevalence, trend, and predictor analyses of vitamin D deficiency in the US population, 2001-2018. Front Nutr. 2022;9:965376.
Ross AC, Manson JE, Abrams SA, et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011;96:53-8.
Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96:1911-30.
Manson JE, Brannon PM, Rosen CJ, et al. Vitamin D deficiency-is there really a pandemic. N Engl J Med. 2016;375:1817-20.
Conti G, Chirico V, Lacquaniti A, et al. Vitamin D intoxication in two brothers: be careful with dietary supplements. J Pediatr Endocrinol Metab. 2014;27:763-7.
Holick, Michael, et al. The UV Advantage. Ibooks, 2004.
Holick, Michael F. The Vitamin D Solution: A 3-Step Strategy to Cure Our Most Common Health Problems. Penguin Publishing Group, 2011.
Szabo, Liz. Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It. The New York Times. August 18, 2018.
Lee JM, Smith JR, Philipp BL, Chen TC, Mathieu J, Holick MF. Vitamin D deficiency in a healthy group of mothers and newborn infants. Clin Pediatr. 2007;46:42-4.
Holick MF. Vitamin D deficiency: what a pain it is. Mayo Clin Proc. 2003;78:1457-9.
Passeri G, Pini G, Troiano L, et al. Low Vitamin D Status, High Bone Turnover, and Bone Fractures in Centenarians. J Clin Endocrinol Metab. 2003;88:5109-15.
Armstrong, David. The Child Abuse Contrarian. ProPublica. September 16, 2018.
Irwig MS, Kyinn M, Shefa MC. Fin...
Hookworms: Can parasites improve your health?
Normal Curves: Sexy Science, Serious Statistics
05/05/25 • 68 min
What if you could treat your prediabetes with . . . worms? Regina and Kristin dive into a surprising early-phase clinical trial on hookworm therapy—that’s right, intentionally infecting yourself with parasitic worms—to treat metabolic conditions. They dig into the biological rationale (inflammation, abdominal fat, and gut immunology), the clever study design (hello, Tabasco sauce!), and the statistical chops behind this phase 1B trial (block randomization, missing data, and nonparametric hypothesis tests). Along the way, expect self-experimenting scientists, worm sex, poop analysis, and the world’s nerdiest aphrodisiac: a well-documented protocol.
Statistical topics
- Randomized controlled trial (RCT)
- Primary and secondary outcomes
- Placebos, placebo effect, and nocebo effect
- Block randomization
- Sample size
- Double-blinding
- Missing data protocols
- Reproducible research
- Nonparametric hypothesis testing
- Kruskal-Wallis test
Methodological morals
- “Walk before you can run. Invest in simple but high-quality Phase I clinical trials.”
- “When faced with small samples, you better rank and sum, baby.”
References
- Pierce DR, McDonald M, Merone L, et al. Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes. Nat Commun. 2023;14(1):4503. doi:10.1038/s41467-023-40263-4
- Nuzzo, R. What Happens When Scientists Experiment on Themselves? Reader’s Digest. Updated April 16, 2016.
- Ethics of self-experimentation
- Helminthic Therapy Wiki
- Pritchard D. Worming your way to good health [video online]. TEDx Talks. Published November 19, 2013. https://www.youtube.com/watch?v=sm5DcdZbnGA
- Chapman PR, Giacomin P, Loukas A, McCarthy JS. Experimental human hookworm infection: a narrative historical review. PLoS Negl Trop Dis. 2021;15(12):e0009908. doi:10.1371/journal.pntd.0009908
- Sobotková K, Parker W, Levá J, Růžková J, Lukeš J, Jirků Pomajbíková K. Helminth Therapy - From the Parasite Perspective. Trends Parasitol. 2019;35(7):501-515. doi:10.1016/j.pt.2019.04.009
- Zatterale F, Longo M, Naderi J, et al. Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes. Front Physiol. 2020;10:1607. Published 2020 Jan 29. doi:10.3389/fphys.2019.01607
Kristin and Regina’s online courses
Demystifying Data: A Modern Approach to Statistical Understanding
Clinical Trials: Design, Strategy, and Analysis
Medical Statistics Certificate Program
Epidemiology and Clinical Research Graduate Certificate Program
Program we teach in:
Epidemiology and Clinical Research Graduate Certificate Program
Find us on:
Kristin - LinkedIn & Twitter/X
Regina - LinkedIn & ReginaNuzzo.com
- (02:44) - What happens when scientists experiment on themselves
- (06:56) - Mail-order DIY helminthic therapy
- (09:26) - Hookworm biology
- (15:53) - Inflammation, abdominal fat, immune system, and hookworms
- (21:29) - Hookworm therapy clinical trial design
- (26:00) - Clinical trial phases deep dive
- (31:24) - Interesting placebos (sham surgeries and psychedelics)
- (37:33) - Excitement over hookworm trial open data an...
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FAQ
How many episodes does Normal Curves: Sexy Science, Serious Statistics have?
Normal Curves: Sexy Science, Serious Statistics currently has 9 episodes available.
What topics does Normal Curves: Sexy Science, Serious Statistics cover?
The podcast is about Alcohol, Fashion, Society & Culture, Sex, Science Podcast, Dating, Medicine, Data Visualization, Fitness, Podcasts, Science, Relationships, Drinking, Math and Data Science.
What is the most popular episode on Normal Curves: Sexy Science, Serious Statistics?
The episode title 'Sugar Sag: Is Your Diet Aging You?' is the most popular.
What is the average episode length on Normal Curves: Sexy Science, Serious Statistics?
The average episode length on Normal Curves: Sexy Science, Serious Statistics is 55 minutes.
How often are episodes of Normal Curves: Sexy Science, Serious Statistics released?
Episodes of Normal Curves: Sexy Science, Serious Statistics are typically released every 14 days.
When was the first episode of Normal Curves: Sexy Science, Serious Statistics?
The first episode of Normal Curves: Sexy Science, Serious Statistics was released on Feb 13, 2025.
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