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Night Science
Itai Yanai & Martin Lercher
Where do ideas come from? In each episode, scientists Itai Yanai and Martin Lercher explore science's creative side with a leading colleague. New episodes come out every second Monday.
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Top 10 Night Science Episodes
Goodpods has curated a list of the 10 best Night Science episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Night Science for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Night Science episode by adding your comments to the episode page.
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11/25/24 • 50 min
In this episode, Stanford professor Michael Fischbach discusses insights from his course on how to choose meaningful research problems. Highlights include:
- Invest time in problem selection: Spend more time upfront selecting the right research problem.
- Date ideas: Before settling on an idea, explore multiple alternatives without emotional attachment.
- Fixed vs. floating parameters: Early on, clearly define what aspects of your research idea are fixed and which can be flexible.
- Manage risks: Embrace risk but systematically de-risk projects.
- Killer experiments: Identify early “go/no-go” experiments.
- Turn crises into opportunities: Use a project's crisis to find out what it's really about.
This episode was supported by Research Theory (researchtheory.org). For more information about Night Science, visit https://www.biomedcentral.com/collections/night-science .
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67 | A hypothesis is a liability
Night Science
12/16/24 • 39 min
In this episode, Itai and Martin delve into the interplay between hypothesis-driven and exploratory research, drawing on insights from past guests of the Night Science Podcast. They discuss how being focused on a single hypothesis can prevent us from making discoveries, while emphasizing the value of open-ended exploratory analyses—often dismissed as “fishing expeditions.” The episode also examines the risks inherent to both approaches: hypothesis-driven Day Science may overlook key insights, while exploratory Night Science risks being misled by randomness.
This episode was supported by Research Theory (researchtheory.org).
For more information about Night Science, visit https://www.biomedcentral.com/collections/night-science .
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Trailer
Night Science
04/20/21 • 5 min
In this 5-minute trailer, your hosts Itai Yanai and Martin Lercher explain what the Night Science Podcast is all about: conversations with great scientists about the creativity in their scientific process.
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14 | Bill Martin on paying attention
Night Science
02/24/22 • 39 min
Professor Bill Martin from Düsseldorf University is a leading evolutionary biologist, who has made fundamental contributions to our understanding of the origins of eukaryotes, the cell nucleus, and life itself. In this episode, Bill reveals how he chooses a research question and boosts his creativity. He also discusses the pitfalls of exploratory data analysis and the perils of working in highly crowded fields. And he challenges us: whenever a visitor gives a talk at your institute – think of the most interesting question. You owe it to the visitor, and it’ll give you ideas.
For more information on Night Science, visit www.night-science.org .
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06/28/21 • 51 min
Yana Bromberg is a Professor at Rutgers, where she teaches computers to speak the functional language of biological sequences. In this episode, she talks with Itai and Martin about the amazing creativity of machine learning, the search for weirdness, and her superpower of translating things from one field to another.
Her work is being recognized from virtually all sides, including NASA and NIH. She has received a CAREER award from the National Science Foundation. Yana asks deep fundamental questions whose answers are very important for improving our health, preserving our environment, and, as she writes on her website, also to figure out if “Well... did we really start as green slime?!”
For more information on Night Science, visit www.night-science.org
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21 | Daniel Kahneman and the sunk-cost fallacy
Night Science
09/22/22 • 43 min
Daniel Kahneman won the Nobel Prize for Economics – as a psychologist. His fundamental work in behavioral economics revealed our cognitive biases, such as loss aversion – the fact that we react much more strongly to losses than to gains. Danny’s popular science book “Thinking, Fast and Slow” is a highly influential bestseller; Itai and Martin consider it the operating manual for the human brain. In this conversation, Danny tells us how his creative process is driven by a lack of content with what has already been achieved. Other topics we talk about include the suspension of critical weapons, why anthropomorphisms are valuable, how to give the mind something to work on while asleep, and Danny’s innovation of the ‘adversarial collaboration’.
For more information on Night Science, visit https://www.biomedcentral.com/collections/night-science .
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04/10/23 • 61 min
In this special, we talk about podcasting with the two hosts of the Big Biology Podcast (https://www.bigbiology.org), Marty Martin – professor of disease ecology at the University of South Florida – and Art Woods – professor of physiological ecology at the University of Montana. We had a great time discussing our respective podcast experiences, trading tips and reflecting on our passion for science communication and the ways that it has impacted our own research. In their podcast, Marty and Art tell the stories of scientists tackling some of the biggest unanswered questions in biology. While both of our podcasts focus on the people doing science, Big Biology discusses the results, while Night Science explores the creative process of science.
For more information on Night Science, visit https://www.biomedcentral.com/collections/night-science .
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16 | Agnel Sfeir on science as an obsession
Night Science
05/16/22 • 42 min
Agnel Sfeir is a leading scientist in the Memorial Sloan Kettering Cancer Center in New York, who studies fundamental aspects of the biology of the cell. Agnel revels in asking seemingly simple questions that get to the heart of the unknown in biology. In this conversation, she told us how she immerses herself in the project together with her team, and learns how to mentor each person depending on how they like to think. She discusses the trick of ‘thinking selfishly’ for generating ideas: when reading or listening to something, you should constantly think about how it might be related to your project. She generates new insights by obsessing about a particular problem in her research, blurring the line between day and night. In the last minutes of our conversation, she revealed to us how it is almost always during the last five minutes of a meeting when the most important insights emerge.
For more information on Night Science, visit www.night-science.org .
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10/30/23 • 42 min
Christina Curtis is a Professor of Medicine and the Director of Artificial Intelligence and Cancer Genomics at Stanford University’s Cancer Institute. Among her many achievements is the conception of the “Big Bang Theory” of tumor biology. In this episode, she tells us how not being biased by assumptions of what we know has been very helpful in her research. We talk about how her background in statistical genetics has shaped her cancer research. We also discuss how the despair of not understanding is a phase that occurs in almost any research project, and we discuss the use of generative AI in the creative scientific process.
For more information on Night Science, visit https://www.biomedcentral.com/collections/night-science .
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02/17/25 • 45 min
Meghan O'Rourke, acclaimed author of The Invisible Kingdom, poet, and Yale professor, joins us to explore the parallels between creative writing and scientific discovery. She describes how deep immersion in a project attracts unexpected insights, and she introduces Night Poetry and Day Poetry, inspired by our concepts of Night Science and Day Science—where night represents raw creation and day embodies refinement. We discuss how scientists and writers face similar challenges: questioning assumptions, balancing structure with spontaneity, and finding meaning in unexpected connections. Through Meghan's insights, we discover how creativity manifests similarly across disciplines, and how being an outsider can often lead to fresh perspectives.
For more information about Night Science, visit https://www.biomedcentral.com/collections/night-science .
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FAQ
How many episodes does Night Science have?
Night Science currently has 71 episodes available.
What topics does Night Science cover?
The podcast is about Life Sciences, Creativity, Natural Sciences, Podcasts, Science, Philosophy and Biology.
What is the most popular episode on Night Science?
The episode title '66 | Michael Fischbach and the scientific decision tree' is the most popular.
What is the average episode length on Night Science?
The average episode length on Night Science is 38 minutes.
How often are episodes of Night Science released?
Episodes of Night Science are typically released every 14 days, 10 hours.
When was the first episode of Night Science?
The first episode of Night Science was released on Apr 20, 2021.
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