Mind Control with Lasers: Optical Recording Part II

Welcome back to Neurotech Pub!

This episode is part two of a two part series on optical methods for recording and stimulating neural activity. Our guests on this episode are Elizabeth Hillman, PhD, Mark Schnitzer, PhD, and Jacob Robinson, PhD. Last time we talked about optical recording methods, but in this episode we focus on optical stimulation methods.

Cheers!

Check out video and full transcript here: https://www.paradromics.com/podcast/episode-12-mind-control-with-lasers

00:00 | Intro

1:37 | Aspirational Papers

1:56 | Packer Lab

2:10 | What is the claustrum?

2:30 | Ian's paper (but only part of it!)

3:02 | Two-Photon Bidirectional Control and Imaging In Vivo

3:29 | Inferring Spikes from Calcium Imaging

5:45 | Neuropixels are now in humans

7:12 | Paper by Pachitariu et al

7:55 | Ian Oldenburg

10:02 | Kaufman Lab

11:21 | Cortical activity in the null space: permitting preparation without movement

12:08 | Motor cortical dynamics shaped by multiple distinct subspaces during naturalistic behavior

12:33 | Tickling Cells with Light

14:41 | Light-activated ion channels for remote control of neuronal firing

14:50 | Remote Control of Behavior through Genetically Targeted Photostimulation of Neurons

15:20 | Millisecond-timescale, genetically targeted optical control of neural activity

16:03 | Red-shifted Opsins

16:52 | eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications

17:26 | Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor

18:16 | Neural Dust

18:41 | Wireless magnetothermal deep brain stimulation

19:05 | Neural Stimulation Through Ultrasound

19:20 | Methods and Modalities: Sculpting Light

21:35 | Recent advances in patterned photostimulation for optogenetics

22:50 | Two-photon microscopy is now over 30 years old (Denk 1990)

25:22 | Optical Recording State of the Art

27:06 | Challenges of Deep Tissue 2-Photon Imaging

28:21 | Deisseroth Lab

28:29 | Temporal Precision of Optical Stimulation

29:09 | Simultaneous all-optical manipulation and recording

30:40 | Targeted Ablation in Somatosensory Cortex

33:29 | Commercial...