
Business Models in Neurotech
03/03/22 • 105 min
Welcome back to the Season 2 premiere of Neurotech Pub!
In this episode, host and Paradromics CEO Matt Angle sits down with fellow Founder/CEOs Carolina Aguilar, Brian Pepin, and Kunal Ghosh to talk shop about building cutting edge neurotech companies from the ground up. We dive deep into business strategies, the neurotech fundraising landscape, emerging therapeutics, and more. We also provide an insider’s view of the intersections of data, pharma, and med devices that are shaping the future of healthcare. Pour yourself a cold one and settle in!
Check out full video with transcript here: Check out video and a full episode transcript here.
00:00 | Updates & News
>> INBRAIN Neuroelectronics raised a $17M Series A
>> Rune Labs raised a $22.8 Million Series A
>> Inscopix Launched Cloud-Based Platform for Data Management and Analysis
2:15 | Meet the panel and pick up a book
1:54 | Jester King Brewery
2:25 | Rune Labs
2:50 | Neurostimulator for deep brain stimulation therapy
3:23 | INBRAIN Neuroelectronics
4:11 | Inscopix
5:24 | Ursula K. Le Guin’s 'The Dispossessed'
6:19 | Yuval Noah Harari’s 'Sapiens: A Brief History of Humankind'
6:32 | Daniel G. Miller’s 'The Tree of Knowledge'
6:40 | Jiddu Krishnamurti’s 'The Book of Life'
7:34 | Barack Obama’s 'A Promised Land,' ‘Dreams from my Father,’ & ‘The Audacity of Hope’ 7:56 | Karl Popper’s 'The Open Society and Its Enemies'
9:25 | Venture Capital in Neurotech
34:44 | Business Strategy in Neurotech
40:32 | Tom Oxley, CEO, Synchron
43:58 | Dr. Thomas Insel
44:06 | Mindstrong Mental Health Care
44:35 | Aduhelm controversy
52:25 | Galvani Bio
59:39 | Percept Neurostimulator
1:00:32 | Neuromodulation and the future of treating brain disease
1:07:21 | Software as a Medical Device FDA Guidance
1:09:12 | State of Animal Model Systems
1:14:28 | α-Synuclein in Parkinson's Disease
1:18:01 | Alto Neuroscience
1:18:36 | Flatiron Foundation
1:18:45 | Gaurdent Health
1:19:...
Welcome back to the Season 2 premiere of Neurotech Pub!
In this episode, host and Paradromics CEO Matt Angle sits down with fellow Founder/CEOs Carolina Aguilar, Brian Pepin, and Kunal Ghosh to talk shop about building cutting edge neurotech companies from the ground up. We dive deep into business strategies, the neurotech fundraising landscape, emerging therapeutics, and more. We also provide an insider’s view of the intersections of data, pharma, and med devices that are shaping the future of healthcare. Pour yourself a cold one and settle in!
Check out full video with transcript here: Check out video and a full episode transcript here.
00:00 | Updates & News
>> INBRAIN Neuroelectronics raised a $17M Series A
>> Rune Labs raised a $22.8 Million Series A
>> Inscopix Launched Cloud-Based Platform for Data Management and Analysis
2:15 | Meet the panel and pick up a book
1:54 | Jester King Brewery
2:25 | Rune Labs
2:50 | Neurostimulator for deep brain stimulation therapy
3:23 | INBRAIN Neuroelectronics
4:11 | Inscopix
5:24 | Ursula K. Le Guin’s 'The Dispossessed'
6:19 | Yuval Noah Harari’s 'Sapiens: A Brief History of Humankind'
6:32 | Daniel G. Miller’s 'The Tree of Knowledge'
6:40 | Jiddu Krishnamurti’s 'The Book of Life'
7:34 | Barack Obama’s 'A Promised Land,' ‘Dreams from my Father,’ & ‘The Audacity of Hope’ 7:56 | Karl Popper’s 'The Open Society and Its Enemies'
9:25 | Venture Capital in Neurotech
34:44 | Business Strategy in Neurotech
40:32 | Tom Oxley, CEO, Synchron
43:58 | Dr. Thomas Insel
44:06 | Mindstrong Mental Health Care
44:35 | Aduhelm controversy
52:25 | Galvani Bio
59:39 | Percept Neurostimulator
1:00:32 | Neuromodulation and the future of treating brain disease
1:07:21 | Software as a Medical Device FDA Guidance
1:09:12 | State of Animal Model Systems
1:14:28 | α-Synuclein in Parkinson's Disease
1:18:01 | Alto Neuroscience
1:18:36 | Flatiron Foundation
1:18:45 | Gaurdent Health
1:19:...
Previous Episode

Building (and Funding) Neurotech Companies
Welcome to the Season 1 finale of Neurotech Pub!
In this episode, host and Paradromics CEO, Matt Angle, speaks with fellow Neurotech CEOs, Konstantinos Alataris, Frank Fischer, and Marcus Gerhardt.
"We cover a lot in this discussion, but one of the big themes is how challenging it can be to raise money, to build neuro devices. This episode was originally recorded last winter, and it was instantly one of my favorite episodes. So like a fine wine, I laid it down until the time was right to share it with friends.
Since the episode was recorded, Nesos, Paradromics, and BlackRock all had major funding announcements. Nesos and BlackRock underwent rebranding campaigns, and NeuroPace went public on Nasdaq. This podcast was recorded during a bleak winter, but our optimism proved prescient. The podcast aged well, and now the field is the strongest, best funded, and most exciting that it's ever been. I know you'll enjoy the discussion."
- Matt Angle, CEO, Paradromics
Check out full video with transcript here: https://www.paradromics.com/podcast/neurotech-pub-episode-9-building-and-funding-neurotech-companies
01:08 | Meeting Heros
08:02 | Company Origins: NeuroPace, Blackrock Neuro, and Nēsos
25:28 | Now vs Then, a Decade of Neurotech Entrepreneurship
1:04:50 | Investor Backing in Neurotech
1:20:44 | BCI Future Is Underway
Want more?
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Next Episode

Let there be Light: Optical Recording Part I
Welcome back to Neurotech Pub!
This episode is one of a two part series on optical methods for recording and stimulating neural activity. Our guests on this episode are Elizabeth Hillman, PhD, Mark Schnitzer, PhD, and Jacob Robinson, PhD. So far, our technical dives have focused mainly on direct electrical recording and stimulation of neural activity, but in this episode we deep dive into advantages that all-optical interfaces might have over electrical interfaces, and the challenges in developing them.
In addition, we talk about running highly collaborative, interdisciplinary projects that span traditional physics and engineering with biology, a theme that is ever-present in neurotech and is also highlighted in part two of this series.
Cheers!
Check out full video with transcript here: https://www.paradromics.com/podcast/episode-11-let-there-be-light
Show Notes
Latest news & publications since recording:
>> Hillman Lab: New publication on SCAPE in Nature Biomedical Engineering
>> Robinson Lab: Review article in Optica on Recent advances in lensless imaging
>> Robinson Lab: BioRxiv pre-print on in vivo fluorescence imaging
1:23 | The Heart and Soul of a Paper
2:32| Ultrasmall Mode Volumes in Dielectric Optical Microcavities
3:01 | Robinson Lab
4:01 | Hillman Lab
4:07 | Zuckerman Institute
4:15 | Schnitzer Lab
4:25 | Howard Hughes Medical Institute
4:41| Miniature Fluorescence Microscope
9:02 | Discovery of DNA Structure and Function
10:25 | Hodgkin–Huxley Equations
13:49 | Vessel Dilation in the Brain
16:03 | State of the art of Neural Optical Recording
18:03 | Long-Term Optical Access to an Estimated One Million Neurons in Mouse Cortex
24:56 | Watch the Crystal Skull video
27:45 | High-Speed Cellular-Resolution Light Beads Microscopy
29:54 | Relationship between spiking activity and calcium imaging
32:50 | Analytical & Quantitative Light Microscopy [AQLM]
32:59 | Imaging Structure & Function in the Nervous System
35:22 | NIH Brain Initiative Cell Census Network (BICCN)
35:54 | Allen Brain Atlas: Cell Types
40:17 | A Theory of Multineuronal Dimensionality, Dynamics and Measurement
46:19 | Dr. Laura Waller's DIY Diffuser Cam
50:38 | FlatCam by Robinson Lab
53:42 | Advantages of MEG
55:06| Random Access Two Photon Scanning Techniques
56:07 | Swept C...
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