Natural Medicine Podcast

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Carolyn Ledowsky is well-known for her expertise in supporting people with MTHF Single Nucleotide Polymorphisms (SNPs). Carolyn has an urgent callout for all practitioners to help her find suitable candidates for her PhD Trial.
These candidates are your patients who have suffered multiple miscarriages.
There's an upcoming podcast to learn more, but for now, please help in securing enough trial participants so we can get the clearest picture of what works with regard to Folic Acid versus MTHF supplementation.
Link to Trial Participation.
References TBC

This is Part 1 of a several-part series on Integrative Cancer Support. These will be a "must-listen" podcast series for those who care for patients with a cancer diagnosis.
Our expert today is Sarah Franklin who is a naturopath, nutritionist, acupuncturist and registered nurse with specialised training in oncology care.
In this episode, Sarah discusses how her clinical background and her blend of modalities can be employed to best support her patients' through their cancer diagnosis journey. From the first numbing "thump" upon receiving a cancer diagnosis, to the ensuing anxiety over mortality, pain, family, work, finances, organising a patient's support team...and all the things!.
Sarah guides us through the practical aspects of patient care, some of the therapeutic options to consider and how to prioritise and implement interventions that support both their physical and emotional wellbeing. She also helps to clarify the (sometimes many!) medical specialists and their roles and functions in a patient's care team.
In our later episodes we will cover such topics as how different cancer types receive differing integrative cancer support, when to offer supplements and when to "pick up the pieces" after treatment, how to engage with orthodox health professionals who have limited knowledge about naturopathic approaches and how we can offer real and lasting support to those caring for cancer patients.
RESOURCES FROM THIS EPISODE:
Find Sarah at BalancedHealth.com.au
Find Sarah on Facebook
Follow Sarah on Instagram
DISCLAIMER: The Natural Medicine Podcast is intended as professional information for integrative medicine practitioners and as such, must not be taken as medical advice. Patients are expressly directed to seek appropriate care from a suitably qualified practitioner.

In today's episode we explore the paradigms of bias in the natural and orthodox health care profession. As my guest, naturopath Geraldine Headley explains, we need to be aware of how insidiously our unconcious bias to "big nature" may be influencing therapeutic decisions.
In our candid discussion, Geraldine urges practitioners to explore whether pecuniary interests are playing a role in clinical decision making. As a mentor to the complementary medicine profession, I love how Geraldine raises this issue for discussion and brings awareness to the fact that 'big pharma' isn't the only player influencing health care.
Connect with Geraldine Headley
RESOURCES FROM THIS EPISODE:
Vitamin D interactions:
Diamanti-Kandarakis E, Duntas L, Kanakis GA, et al. Drug-induced endocrinopathies and diabetes: a combo-endocrinology overview. Eur J Endocrinol. 2019. 181:R73-R105.
Coenzyme Q10 does not interact with warfarin:
Engelsen J, Nielsen JD, Hansen KFW. [Article in Danish] [Effect of Coenzyme Q10 and Ginkgo biloba on warfarin dosage in patients on long-term warfarin treatment. A randomized, double-blind, placebo-controlled cross-over trial]. Ugeskr Laeger. 2003 Apr 28;165(18):1868-71.
Coenzyme Q10 does interact with warfarin (look closely at the wording!):
Shalansky S, Lynd L, Richardson K, et al. Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis. Pharmacotherapy. 2007 Sep;27(9):1237-47.

Listeners will also get the lowdown on the Bioconcepts Mastering Pathology Summit, to be held on 25-26th October 2024, where Dr. Schloss will present alongside a star-studded lineup of speakers on critical clinic-relevent topics. The event promises to enrich practitioners’ understanding of pathology, explaining the significance of different cancer tests and how such knowledge can be applied in clinical settings. By attending this summit, participants can expect to gain valuable insights to elevate their practice and provide superior patient care, reinforcing the theme of practitioner knowledge directly benefitting patient outcomes.
Get Your Virtual Tickets Now
https://info.bioconcepts.com.au/pathology-summit/pricing?hsCtaTracking=21d48747-d35c-4e36-9015-b3f4af0b48cc%7C70f6b9a1-f874-47ca-9d96-ea59dc52807c#pricing

URGENT MESSAGE: Denise has generously organised a 20% discount for the first 60 people to purchase her upcoming 28 Day WholeFood Challenge course beginning in January 2024:
Use the code: NatMedPodcast20
We're born with a genetic blueprint, including some variations we may have acquired along the way. These variations, called SNPs (short for Single Nucleotide Polymorphisms), influence certain characteristics of our DNA blueprint to change gene expression. What we now know is that diet can have effects on gene expression leading to powerful effects on our health.
And what better clinician to lead us through how to master your genes using food, than Dr Denise Furness.
Strap in and have the rewind button handy. This is an information-packed podcast!References
MCM6 - lactose
MCM6 is located upstream from the LCT gene, which produces the enzyme lactase required to digest lactose. MCM6 influences LCT and lactase expression.
PMID: 11788828, PMID: 12915462, PMID: 15114531
HLA-DQ haplotypes - Gluten
Human leukocyte antigen (HLA system) encodes the Major Histocompatibility Complex (MHC). These genes code for antigens (proteins) that help cells recognise self versus non-self. Genetic variations within HLA-DQA1 & HLA-DQB1 are linked to coeliac disease and other autoimmune conditions.
PMID: 30763397, PMID: 29244800
MTHFR Folate
MTHFR converts 5,10-methylenetetrahydrofolate (5,10 methyleneTHF) to 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is needed to convert homocysteine to methionine, therefore MTHFR supports methylation (making SAM) reactions throughout the body.
MTHFR 677 T allele and increased risk for lower folate and higher homocysteine levels PMID: 25788000, 24091066, 7647779, 9545395
APO-E Alzheimer's, Lipids
APOE’s main phenotypes are caused by the combination of two SNPs that combine to form the genotypes/isoforms of ε2, ε3 and ε4 or E2, E3, E4. The E4 allele is associated with higher LDL levels and cardiovascular and neurological complications.
PMID: 25328986, PMID: 11882522
SLC30A8 - zinc transporter
Specific to pancreatic islets and mainly expressed in β-cells that transport zinc from the cytoplasm into insulin secretory vesicles. Allelic variants have been associated with glucose and pro-insulin levels and confer susceptibility to insulin resistance and diabetes mellitus (T2DM).
PMID: 28218639, 17463249, 30936916.

FTO and MC4R - weight and obesity
Fat mass and obesity-associated gene (FTO)
Melanocortin-4-receptor (MC4R)
PMID: 31954858, 19079261, 26888713