The concept of DNA methylation in Inflammatory Bowel Disease with Dr. Anje te Velde and Prof. Wouter de Jonge

03/13/24 • 16 min

In the first episode of METHYLOMIC matters we will speak with dr. Anje te Velde and Professor Wouter de Jonge, diving into the concept of DNA methylation changes in IBD and their potential to be used as biomarkers of therapy response in IBD. What is epigenetics and how does it work? Why is DNA methylation interesting in complex immune mediated diseases and what is the history behind the EPIC-CD and METHYLOMIC projects? All this and more in the first episode of METHYLOMIC matters!

Next Episode

Pre-METHYLOMIC: results from the EPIC-CD project with prof. Geert D'Haens and dr. Andrew Li Yim

In the second episode of METHYLOMIC matters we have the privilege of conversing with Professor Geert D’Haens and Dr. Andrew Li Yim as we delve into the pre-METHYLOMIC era and discover the science behind the OMICROHN trial: the EPIC-CD study. How did we design this biomarker discovery study and what are key important methodological steps? What were the main results and how do we envision the future? All this and more in the second episode of METHYLOMIC matters!