JACC Specialty Journals

In this episode, Brian Joyce discusses a groundbreaking study that examines the link between DNA methylation and the incidence of cardiovascular disease and cancer across three major cohorts. The research identifies shared epigenetic signatures associated with both diseases, highlighting the need for further investigation into their functional implications and potential clinical applications in diverse populations.

In this episode, Dr. Tochi Okwuosa discusses a pivotal study examining the association between the Life Essential 8 cardiovascular health score and the incidence of cardiovascular disease in women with breast cancer. The research, which followed over 7,000 participants, found that higher scores correlated with significantly lower rates of cardiovascular events, underscoring the importance of cardiovascular health even in cancer patients and highlighting the need for future studies in more diverse populations.

In this episode, Dr. Josh Mitchell reviews a significant study that explores the links between physical health markers, such as waist circumference and hand grip strength, and cardiovascular outcomes in men with prostate cancer undergoing androgen deprivation therapy. The findings indicate that increased waist circumference and decreased grip strength are associated with higher cardiovascular event risks, highlighting the need for targeted interventions like exercise in these patients and emphasizing the importance of further research in diverse populations.

In this episode, Efstratios Koutroumpakis discusses a critical study on autonomic dysfunction among adult survivors of childhood cancer, highlighting its prevalence and functional significance compared to community controls. The research underscores the complex etiologies of autonomic dysfunction linked to cancer treatments and stresses the importance of early detection and standardized testing to improve cardiovascular health and quality of life in this growing survivor population.

Abdullah Al-Abcha, MD, social media editor of JACC: Cardiovascular Interventions, and Sung Gyun Ahn, MD, PhD, discuss a recently published original research paper reporting the outcomes of failed thrombus aspiration in patients with STEMI and large thrombus burden.