
Zero Trust in Action: Revolutionizing Incident Response | A Zero Trust World Conversation with Art Ocain | On Location Coverage with Sean Martin and Marco Ciappelli
02/25/25 • 14 min
At ThreatLocker Zero Trust World 2025 in Orlando, Art Ocain, VP of Cybersecurity & Incident Response at Airiam, shared valuable insights into applying zero trust principles to incident response. The conversation, hosted by Marco Ciappelli and Sean Martin, highlighted the critical role of zero trust in preparing for and managing security incidents.
The Zero Trust Mindset in Incident Response Ocain discussed how zero trust methodology—embracing the principles of "assume breach" and "always verify, never trust"—can significantly enhance incident response strategies. Instead of merely securing the perimeter or endpoints, his approach involves identifying and protecting core systems through micro-segmentation and robust identity management. By securing each component individually, organizations can minimize the impact of potential breaches.
For example, Ocain described a scenario where segmenting a SQL server from an application server could prevent data loss during an attack. Even if an application server is compromised, critical data remains secure, allowing quicker recovery and continuity of operations.
Dynamic Containment Strategies Ocain emphasized the importance of dynamic containment when responding to incidents. Traditional methods, such as using Endpoint Detection and Response (EDR) tools, are effective for forensic analysis but may not stop active threats quickly. Instead, he advocated for an "allow list only" approach that restricts access to systems and data, effectively containing threats while maintaining critical business functions.
In practice, when Ocain is called into a crisis, he often implements a deny-by-default solution to isolate compromised systems. This strategy allows him to perform forensics and bring systems back online selectively, ensuring threat actors cannot access recovered systems.
Balancing Security with Business Needs A significant challenge in adopting zero trust is gaining executive buy-in. Ocain noted that executive teams often push back against zero trust measures, either out of a desire for convenience or because of misconceptions about its impact on business culture. His approach involves demonstrating real-world scenarios where zero trust could mitigate damage during breaches. By focusing on critical systems and showing the potential consequences of compromised identities or systems, Ocain effectively bridges the gap between security and business priorities.
A Cultural Shift Toward Security The discussion also touched on the cultural shift required to fully integrate zero trust into an organization. Zero trust is not just a technological framework but a mindset that influences how every employee views access and security. Through scenario-driven exercises and engaging executive teams early in the process, Ocain helps organizations transition from a "department of no" mentality to a collaborative, security-first culture.
Listen to the full episode to explore more strategies on implementing zero trust in incident response and how to align security initiatives with business goals.
Guest: Art Ocain, VP of Cybersecurity & Incident Response at Airiam | On LinkedIn: https://www.linkedin.com/in/artocain/
Hosts:
Sean Martin, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining CyberSecurity Podcast [@RedefiningCyber] | On ITSPmagazine: https://www.itspmagazine.com/sean-martin
Marco Ciappelli, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining Society Podcast & Audio Signals Podcast | On ITSPmagazine: https://www.itspmagazine.com/itspmagazine-podcast-radio-hosts/marco-ciappelli
____________________________
This Episode’s Sponsors
ThreatLocker: https://itspm.ag/threatlocker-r974
____________________________
Resources
Learn more and catch more stories from ZTW 2025 coverage: https://www.itspmagazine.com/zero-trust-world-2025-cybersecurity-and-zero-trust-event-coverage-orlando-florida
Register for Zero Trust World 2025: https://itspm.ag/threat5mu1
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Catch...
At ThreatLocker Zero Trust World 2025 in Orlando, Art Ocain, VP of Cybersecurity & Incident Response at Airiam, shared valuable insights into applying zero trust principles to incident response. The conversation, hosted by Marco Ciappelli and Sean Martin, highlighted the critical role of zero trust in preparing for and managing security incidents.
The Zero Trust Mindset in Incident Response Ocain discussed how zero trust methodology—embracing the principles of "assume breach" and "always verify, never trust"—can significantly enhance incident response strategies. Instead of merely securing the perimeter or endpoints, his approach involves identifying and protecting core systems through micro-segmentation and robust identity management. By securing each component individually, organizations can minimize the impact of potential breaches.
For example, Ocain described a scenario where segmenting a SQL server from an application server could prevent data loss during an attack. Even if an application server is compromised, critical data remains secure, allowing quicker recovery and continuity of operations.
Dynamic Containment Strategies Ocain emphasized the importance of dynamic containment when responding to incidents. Traditional methods, such as using Endpoint Detection and Response (EDR) tools, are effective for forensic analysis but may not stop active threats quickly. Instead, he advocated for an "allow list only" approach that restricts access to systems and data, effectively containing threats while maintaining critical business functions.
In practice, when Ocain is called into a crisis, he often implements a deny-by-default solution to isolate compromised systems. This strategy allows him to perform forensics and bring systems back online selectively, ensuring threat actors cannot access recovered systems.
Balancing Security with Business Needs A significant challenge in adopting zero trust is gaining executive buy-in. Ocain noted that executive teams often push back against zero trust measures, either out of a desire for convenience or because of misconceptions about its impact on business culture. His approach involves demonstrating real-world scenarios where zero trust could mitigate damage during breaches. By focusing on critical systems and showing the potential consequences of compromised identities or systems, Ocain effectively bridges the gap between security and business priorities.
A Cultural Shift Toward Security The discussion also touched on the cultural shift required to fully integrate zero trust into an organization. Zero trust is not just a technological framework but a mindset that influences how every employee views access and security. Through scenario-driven exercises and engaging executive teams early in the process, Ocain helps organizations transition from a "department of no" mentality to a collaborative, security-first culture.
Listen to the full episode to explore more strategies on implementing zero trust in incident response and how to align security initiatives with business goals.
Guest: Art Ocain, VP of Cybersecurity & Incident Response at Airiam | On LinkedIn: https://www.linkedin.com/in/artocain/
Hosts:
Sean Martin, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining CyberSecurity Podcast [@RedefiningCyber] | On ITSPmagazine: https://www.itspmagazine.com/sean-martin
Marco Ciappelli, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining Society Podcast & Audio Signals Podcast | On ITSPmagazine: https://www.itspmagazine.com/itspmagazine-podcast-radio-hosts/marco-ciappelli
____________________________
This Episode’s Sponsors
ThreatLocker: https://itspm.ag/threatlocker-r974
____________________________
Resources
Learn more and catch more stories from ZTW 2025 coverage: https://www.itspmagazine.com/zero-trust-world-2025-cybersecurity-and-zero-trust-event-coverage-orlando-florida
Register for Zero Trust World 2025: https://itspm.ag/threat5mu1
____________________________
Catch...
Previous Episode

From Demo to Deployment: How A Hands-On Human Approach Transforms Security Implementation | A Conversation with Amanda Makowsky at Zero Trust World 2025 | On Location with Sean Martin and Marco Ciappelli
This episode of the “On Location” series, recorded during ThreatLocker Zero Trust World 2025 in Orlando, features an insightful conversation with Amanda Makowsky, Solution Engineer at ThreatLocker. Amanda shares how ThreatLocker maintains a human touch in cybersecurity while delivering robust solutions for organizations of all sizes.
The Human Element in Technology
Amanda explains how ThreatLocker emphasizes human interaction from the first demo through implementation and beyond. When potential customers engage with ThreatLocker, they are assigned a dedicated Solution Engineer as their technical point of contact. Amanda highlights how this relationship extends beyond the sales process, ensuring partners have continuous support as they mature their security environments. Whether working with small businesses or large enterprises, the focus remains on personalized service and hands-on assistance.
Support That Stands Out
ThreatLocker’s commitment to human-centric support is evident through its 24/7 live helpdesk, staffed by real people in Orlando, Florida. Amanda notes the goal of responding to chat requests within a minute, providing immediate support without relying on bots or automated responses. This approach fosters trust and ensures that customers, regardless of their organization’s size, receive timely and effective help.
Customization and Real-World Impact
Amanda shares how every partner’s environment is unique, requiring tailored solutions to accommodate different software, hardware, and operational needs. She emphasizes the importance of building specific and intentional roles within ThreatLocker’s systems to match the diverse environments of their partners. The impact of this customization is profound, as partners express a sense of security that allows them to “sleep better at night.”
Listen to this episode to explore how ThreatLocker combines technology with human connection, offering a refreshing perspective in the cybersecurity industry.
Guest
🔹 Amanda Makowsky, Solutions Engineer at ThreatLocker | On LinkedIn: https://www.linkedin.com/in/amandamakowsky/
Hosts
🔹 Sean Martin, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining CyberSecurity Podcast [@RedefiningCyber] | On ITSPmagazine: https://www.itspmagazine.com/sean-martin
🔹 Marco Ciappelli, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining Society Podcast & Audio Signals Podcast | On ITSPmagazine: https://www.itspmagazine.com/itspmagazine-podcast-radio-hosts/marco-ciappelli
This Episode’s Sponsor
✅ ThreatLocker: https://itspm.ag/threatlocker-r974
Resources
🔗 Full ZTW 2025 Coverage: https://www.itspmagazine.com/zero-trust-world-2025-cybersecurity-and-zero-trust-event-coverage-orlando-florida
🔗 ITSPmagazine’s Event Coverage Hub: https://www.itspmagazine.com/technology-and-cybersecurity-conference-coverage
🎧 More Redefining CyberSecurity Content: https://www.itspmagazine.com/redefining-cybersecurity-podcast
🎧 More Redefining Society Stories: https://www.itspmagazine.com/redefining-society-podcast
📢 Want to share your Brand Story Briefing as part of our event coverage? Learn More 👉 https://itspm.ag/evtcovbrf
📢 Want Sean and Marco at your event? Let Us Know 👉 https://www.itspmagazine.com/contact-us
Next Episode

Transforming Healthcare: How Innovation is Driving Better Patient Outcomes | A HIMSS 2025 Conversation with Albe Zakes | On Location Coverage with Sean Martin and Marco Ciappelli
In this episode of the On Location series recorded for HIMSS 2025 in Las Vegas, hosts Marco Ciappelli and Sean Martin sit down with Albe Zakes, Director of Strategic Communications at HIMSS, to discuss the transformative impact of technology on healthcare and the upcoming conference’s role in driving innovation. HIMSS, a global society of health and technology professionals, brings together leaders, clinicians, practitioners, and innovators to harness the power of information and technology for improved patient outcomes and expanded access to healthcare.
A Focus on Collaboration Over Expertise
Zakes emphasizes a significant shift in how the HIMSS conference operates. While traditional conferences often rely on a top-down approach with speakers sharing insights, HIMSS is increasingly prioritizing collaboration. The 2025 event will feature expanded networking opportunities and dedicated breaks to foster real-time partnerships and relationships that can extend beyond the conference. The approach underscores the organization’s belief in the “symbiotic triangle” of people, technology, and process—highlighting that technology alone is not enough without empowering the people who use it.
Exploring Key Topics: AI, Cybersecurity, and Health Equity
Artificial intelligence (AI) is set to take center stage at HIMSS 2025, reflecting its transition from a speculative technology to a practical tool reshaping healthcare. With dozens of educational sessions dedicated to AI, the conference will explore how clean data and strong governance are critical to unlocking AI’s potential in improving healthcare delivery.
Cybersecurity is another major focus, with a dedicated Healthcare Cybersecurity Forum and a Cybersecurity Command Center on the exhibit floor. Notably, former U.S. Cyber Command and NSA Director General Paul Nakasone will deliver a keynote on maintaining security in an AI-driven world. The emphasis on cybersecurity aligns with the critical need to protect patient data and maintain trust within the healthcare ecosystem.
Zakes also highlights the Health Equity Forum, which aligns with HIMSS’s mission to ensure that technology advancements translate into equitable healthcare access. The forum will gather leaders from governments and nonprofits worldwide to discuss strategies to improve health equity globally.
Innovation and Emerging Technologies
The conference aims to showcase not only established tech giants like Oracle and AWS but also emerging companies and startups. The “First-Time Exhibitors Pavilion” and the “Emerge Innovation Experience” will offer opportunities for attendees to engage with new technologies and ideas. The Emerge Innovation Experience will feature a pitch contest and networking events for entrepreneurs and investors, driving forward-thinking solutions in healthcare technology.
The Power of People, Technology, and Process
This episode offers a glimpse into the critical themes that will dominate HIMSS 2025, providing valuable insights into how technology, collaboration, and innovation are reshaping healthcare. With thought-provoking discussions on AI, cybersecurity, and health equity, listeners are invited to explore how these advancements impact not only healthcare systems but also society at large. Tune in to hear more about the initiatives and opportunities at HIMSS 2025, and how you can be part of the conversation shaping the future of healthcare.
Guest: Albe Zakes, Director of Strategic Communications at HIMSS | On LinkedIn: https://www.linkedin.com/in/albezakes/
Hosts:
Sean Martin, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining CyberSecurity Podcast [@RedefiningCyber] | On ITSPmagazine: https://www.itspmagazine.com/sean-martin
Marco Ciappelli, Co-Founder at ITSPmagazine [@ITSPmagazine] and Host of Redefining Society Podcast & Audio Signals Podcast | On ITSPmagazine: https://www.itspmagazine.com/itspmagazine-podcast-radio-hosts/marco-ciappelli
____________________________
This Episode’s Sponsors
HITRUST: https://itspm.ag/itsphitweb
____________________________
Resources
Learn more and catch more stories from HIMSS 2025 coverage:
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