Infectious Disease Puscast

On episode #37 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/31 – 9/13/23.

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• Association between varicella zoster virus and dementia (NS)
• Safety, efficacy, and immunogenicity of V160 vaccine in cytomegalovirus-seronegative women (The Lancet)
• Microorganisms detected in intussusception cases and controls in children (OFID)
• Clinician testing and treatment thresholds for management of UTIs (OFID)
• Clinical outcomes and management of NAAT-positive/toxin-negative Clostridioides difficile infection (CID)
• Associations of standard care, intrathecal antibiotics, and antibiotic impregnated catheters with cerebrospinal fluid shunt infection (JPIDS)
• Advances in asynchronous telemedicine call for increased antibiotic surveillance (CID)
• Two artificial tears outbreak-associated cases of extensively drug-resistant Pseudomonas aeruginosa detected through whole genome surveillance (JID)
• Pre-XDR congenital TB in an extremely premature baby (CID)
• Emerging Roles of (1→3)-β-D-glucan in cerebrospinal fluid for detection and therapeutic monitoring of fungal diseases (CID)
• Outbreak of locally acquired mosquito-transmitted malaria (CDC)
• Complexity of infectious diseases compared to other cognitive medical subspecialties (OFID)
• Risk of opportunistic infections associated with long-term glucocorticoid therapies in adults (CID)

Music is by Ronald Jenkees

On the the second episode of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 4/27/22 – 5/11/22.

Hosts: Daniel Griffin and Sara Dong

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•Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022(MMWR) •Case Series of False-Positive HIV Test Results in Pediatric Acute Lymphoblastic Leukemia Patients Following Chimeric Antigen Receptor T-Cell Therapy: Guidance on How to Avoid and Resolve Diagnostic Dilemmas (J IDSA) •Immunological correlates of prevention of the onset of seasonal H3N2 influenza (JID) •Use of a Modified Preexposure Prophylaxis Vaccination Schedule to Prevent Human Rabies: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022 (MMWR) •Long-term Safety and Immunogenicity of a Tetravalent Dengue Vaccine Candidate in Children and Adults(MMWR) •The Role of C-Reactive Protein as a Triage Tool for Pulmonary Tuberculosis in Children (J PIDS) •Factors Potentially Contributing to the Contamination of Packaged Leafy Greens Implicated in the Outbreak of Salmonella Typhimurium During the Summer of 2021 (FDA) •Short-course intravenous antibiotics for young infants with urinary tract infection (Arch Dis Children) •Real-World Comparison of Bezlotoxumab to Standard of Care Therapy for Prevention of Recurrent Clostridioides difficile Infection in Patients at High Risk for Recurrence (Clin Inf Dis) •2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults (Clin Inf Dis) •Treatment outcomes 24 months after initiating short, all-oral bedaquiline-containing or injectable-containing rifampicin-resistant tuberculosis treatment regimens in South Africa (Lancet) •Use of Novel Strategies to Develop Guidelines for Management of Pyogenic Osteomyelitis in Adults (JAMA) •Persistent MRSA Bacteremia: Resetting the Clock for Optimal Management (Clin Inf Dis) •Frequency and Duration of, and Risk Factors for, Diagnostic Delays Associated with Histoplasmosis (J Fungi) •Intestinal parasitic infections and associated factors among people living with HIV attending Dessie Referral Hospital, Dessie town, North-east Ethiopia (AIDS Res Ther) •Association of zoonotic protozoan parasites with microplastics in seawater and implications for human and wildlife health (Nat Sci Rep) •Climate change increases cross-species viral transmission risk (Nature and TWiV 898)

Intro music is by Ronald Jenkees Send your questions for Puscast to [email protected]

On episode #29 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/11 – 5/23/23.

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• Harmonie phase IIIb study trial results of nirsevimab against RSV lower respiratory tract infection hospitalization for infants (ESPID)
• Mogamulizumab for treatment of HTLV-1 associated Myelopathy/Tropical Spastic Paraparesis (IDSA)
• Revised protocol for secondary prevention of congenital cytomegalovirus infection with valaciclovir (IDSA)
• Increase in false positive fourth generation HIV tests in patients with COVID-19 (CID)
• Implementation of an antibiotic stewardship initiative in a large urgent care network (JAMA)
• Clindamycin + vancomycin versus linezolid for treatment of necrotizing soft tissue infection (OFID)
• Assessing empiric antimicrobial therapy with the dundee classification for skin and soft tissue infections (OFID)
• Combination of amoxicillin 3000mg and probenecid vs 1500mg amoxicillin monotherapy for treating syphilis in patients with HIV (CID)
• The sympathetic nervous system is necessary for development of CD4+ T cell memory following Staphylococcus aureus infection (JID)
• Efficacy and safety of sulbactam-durlobactam versus colistin for the treatment of patients with infections caused by Acinetobacter baumannii-calcoaceticu complex (The Lancet)
• First reported US cases of tinea caused by Trichophyton indotineae (CDC)
• How to use direct microscopy for diagnosing fungal infections (CMI)
• Limited Cutaneous Leishmaniasis as Ulcerated Verrucous Plaque on leg (EID)
• Can Ivermectin kill Sarcoptes scabiei during the molting process? (PLOS)
• The Infectious Diseases Specialist, at risk of extinction (JID)
• Ticks harbor and excrete chronic wasting disease prions (NIH)

Music is by Ronald Jenkees

On episode #28 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/26 – 5/10/23.

Hosts: Daniel Griffin and Sara Dong

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• Unprecedented outbreak of West Nile Virus (CDC)
• Approval of first RSV vaccine approved for individuals 60 years and older (FDA)
• FDA approves orally administered fecal microbiota product for the prevention of recurrence of C-difficile (FDA)
• Using thermal imaging to track cellulitis (OFID)
• Burden of Typhoid and Paratyphoid fever in India (NEJM)
• Early switch to oral antimicrobials in brain abscess (CMI)
• Considering vancomycin alternatives for pediatric methicillin-resistant Staphylococcus aureus bacteremia (JPIDS)
• Navigating treatment options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus complex infections (CID)
• 2023 Duke-ISCVID criteria for infective Endocarditis (CID)
• Molecular characterization of Candida auris outbreak isolates in Qatar from COVID-19 patients (CMI)
• Amplicon sequencing reveals complex infection in infants congenitally infected with Trypanosoma cruzi (JID)
• Impact of Sequestration on Artemisinin-Induced Parasite Clearance in Plasmodium falciparum Malaria (CID)
• Advances in artificial intelligence for infectious disease surveillance (NEJM)

Music is by Ronald Jenkees

On episode #34 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/20 – 8/2/23.

Host: Daniel Griffin

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• FDA approves first treatment for molluscum contagiosum (FDA)
• Identifying children likely to benefit from antibiotics for Acute Sinusitis (JAMA)
• Impact of metagenomic next-generation sequencing of plasma cell-free DNA testing in patients with suspected infectious diseases (OFID)
• Impact of infectious diseases consultation in patients with candidemia at a multisite healthcare system (OFID)
• Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID)
• Seroprevalence of Chagas disease among people of Latin American descent (AJTMH)
• Malaria transmission-blocking vaccines Pfs230D1-EPA and Pfs25-EPA in Alhydrogel in healthy Malian adults (The Lancet)
• The human blood fluke, Schistosoma mansoni, harbors bacteria throughout the parasite’s life cycle (JID)
• Health care provider knowledge regarding Alpha-gal syndrome (CDC)

Music is by Ronald Jenkees