S2.E3: The Big Leap

01/27/22 • 41 min

The process of moving from a potential drug molecule to being on the shelf of a pharmacy is a long and winding journey. On average, from the time the molecule is discovered to when it's actually approved by the FDA, it takes 12 to 15 years. More importantly, it costs close to $1 billion to bring a drug to market. It's also estimated that of the 1000s of molecules that are looked at, only a few will make it to clinical development, and following that, only five to six percent will survive and ended up being submitted for regulatory review. So how do we choose the winning horse? On this episode of the I'm Pharmacy Podcast we talk to Leslie Dan Faculty of Pharmacy researchers Professor Micheline Piquette Miller, Professor Raymond Reilly, and Dr. Jennifer Doucet on just what it takes to conduct translational research, and the excitement of seeing one's research leave the lab.

Previous Episode

S2.E2: On Target

On this episode of the I'm Pharmacy Podcast, host Mina Tadrous finds answers to the questions: How do we figure out how where drugs work? Does this ever change? And are there more than just one way to find that final target? Featuring discussions with Stèphane Angers, Director and Professor of U of T's Donnelly Centre, and Rob Bonin, Assistant Professor at the Leslie Dan Faculty of Pharmacy and Co-director of the U of T Centre for the Study of Pain.

Next Episode

S2.E4: Perfect Form

How do we pick how to introduce the right molecule into the body in the right way? Well, there's a lot of things to consider. How was it absorbed into the body? Where and how is it broken down? What's the size of the molecule? What is it treating? And where do we want it to go? There's lots of different questions to determine the right formulation. So today we explore the magic of formulations. Why is it important? How do we decide from a laundry list of different medications formulations And how do we develop new formulations that haven't yet been developed?