Future Pulse Cardiology
Thomas Nero MD FACC
Investigating Innovative Cardiovascular Research at the Intersection of Academic Theory and Clinical Practice. In these discussions we take a deep dive into the latest research and how it informs current practice. For a patient level discussion, please listen to PATIENT PULSE. Available on Apple Podcasts, Spotify, YouTube and most other services. Subscribe to have new podcasts sent directly to your player and please email us with any comments. We would love to hear from you.
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Top 10 Future Pulse Cardiology Episodes
Goodpods has curated a list of the 10 best Future Pulse Cardiology episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Future Pulse Cardiology for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Future Pulse Cardiology episode by adding your comments to the episode page.
Coronary Inflammation Imaging with FAI Score on CT angiography with Prof. Stefan Neubauer
Future Pulse Cardiology
06/23/24 • 45 min
We would love to hear your thoughts on the episodes!
Prof. Stefan Neubauer and Dr. Thomas Nero discuss two recent papers on the utility of coronary inflammation imaging on CT coronary angiography with Fat Attenuation Index (FAI)FAI score. The ORFAN study demonstrated a 20 fold increased risk in CV event rates with low vs high FAI score and a 10 fold increased event rate in patients with elevated FAI score who have no coronary plaque. FAI score re-categorized 40% of patients in their follow-up studies.
Prof. Neubauer is the head of the Division of Cardiovascular Medicine and Director of the Oxford Centre for Clinical Magnetic Resonance Research (OCMR) at the University of Oxford and Past President of the Society for Cardiovascular Magnetic Resonance (SCMR). We discussed two recently published landmark papers from his division:
Kenneth Chan, Elizabeth Wahome , et al. Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study. Lancet. 2024;403(10392):1823-1835. doi:10.1016/S0140-6736(24)00596-8
Christopher J. Farina, Michael H. Davidson, Prediman K. Shah, Charles Stark, Wenqi Lu, Cheerag Shirodaria, Timothy Wright, Charalambos A. Antoniades, Jan Nilsson and Nehal N. Mehta (2024). Inhibition of oxidized low-density lipoprotein with orticumab inhibits coronary inflammation and reduces residual inflammatory risk in psoriasis: a pilot randomized, double-blind placebo-controlled trial. Cardiovascular Research, European Society of Cardiology, March 25, 2024.
Anticoagulation, Thombin Generation and Factor XI inhibition in ACS and Atrial Fibrillation with Dr C. Michael Gibson
Future Pulse Cardiology
06/25/23 • 30 min
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Dr. Thomas Nero discusses current therapy with Factor X inhibitors, the new research with Factor XI inhibition and specifically the enrolling Milvexian clinical trials with Dr. C Micahel Gibson. In addition they discuss, the addition of these medications along wiht anti-platelet therapy, Lp(a) and other interesting current and future research in cardiovascular disease.
Diabetes and Cardiovascular Disease, SGLT2 inhibitors and GLP1 receptor agonists with Dr. Peter Toth
Future Pulse Cardiology
05/04/23 • 45 min
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Dr. Thomas Nero speaks with Dr Peter Toth about the dramatic change occuring in diabtetes management and its effect on cardiovascular disease. Starting with the biochemestry of diabetes and its effects at the cellular level, the discussion goes on to speak about the role SGLT2 inhibitors and GLP1 receptor agonists play in DM management as well as the future of diabetes care. (If you want to skip the excelllent, but quite deep dive into biochemistry, jump to 11:22 - but honestly Dr. Toth's description is breathtaking)
Inflammation and Coronary Artery Disease with Dr Paul Ridker
Future Pulse Cardiology
04/09/23 • 40 min
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Dr Paul Ridker discusses his paper on residual inflammatory risk that was recently published in the Lancet with Dr. Thomas Nero. He discusses the pathology of inflammation as part of atherosclerosis, utilization of hs-CRP in clinical trials and in daily practice as well as current therapeutic options and ongoing investigations.
Pragmatic Clinical Trials and EVOLVE-MI with Dr Christopher Cannon
Future Pulse Cardiology
12/12/22 • 21 min
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Dr Christopher Cannon discusses the potential of Pragmatic Clinical Trials in our research armamentarium with Dr. Thomas Nero. They review the EVOLVE-MI trial for Early use of Evolocumab after Myocardial Infarction in detail and highlight the potential for future research.
Spontaneous Coronary Artery Dissection (SCAD) with Dr. Sharonne Hayes Part 2
Future Pulse Cardiology
08/20/22 • 23 min
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Dr Sharoanne Hayes and Dr. Thomas Nero continue their discussion of SCAD focusing on genetics, trial design and the role of online registries as well as the holistic treatment of the SCAD patient. This is part two of two.
Spontaneous Coronary Artery Dissection (SCAD) with Dr. Sharonne Hayes Part 1
Future Pulse Cardiology
08/20/22 • 26 min
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Dr Sharonne Hayes of the May Clinic discusses SCAD with Dr. Thomas Nero. Initially focusing on the new treatment paradigms, their wide ranging discussion covers etiology, pathophysiology and potential future therapeutic options. Tis is the first of a two part podcast.
Evaluation of Coronary Inflammation with CT angiography and Fat Attenuation Indexing
Future Pulse Cardiology
05/05/22 • 28 min
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Dr. Nero discusses evaluation of coronary artery disease and coronary inflammaiton with Dr. Cheerag Shirodaria from the University of Oxford. Dr. Shirodaria along with Prof. Charalambos Antonidies at Caristo Diagnostics have developed a ground breaking technology that allows us to evaluate not just the severity of a coronary artery lesion, but also how inflamed it is and how likely it is to cause fatal and non-fatal myocardial infarction. In addition, since it is a biologically active "marker" the Fat Attenuation Index (FAI) can also be used a a way to evaluate success of medical intervention. Using computer post processing from standard 64 or 128 slice CT coronary angiography, they have been able to evaluate not just the vulnerable patient but also (possibly) the vulnerable plaque.
Legal Aspects of FDA approval and implications for clinical research
Future Pulse Cardiology
04/20/22 • 23 min
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Prof. Christine Coughlin of Wake Forest School of Law speaks with Dr. Thomas Nero on the FDA approval process, emergency use authorization, Right to Try Legislation and the implications for clinical research, diversity and health care equity. Prof. Coughlin holds positions in the College of Medicine as well as the Law school and in the Center for Bioethics. She has published extensively on the FDA approval process.
Lipids, Lipid Sub-fractionations and Inflammation, Putting It All Together with Dr Peter Toth
Future Pulse Cardiology
04/16/23 • 34 min
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Dr. Thomas Nero speaks with Dr. Peter Toth about the complex biology of lipids and atherosclerosis. In this episode Dr Toth dives into LDL goals, therapies for attenuating non-LDL risk, vascular biology and the where are research studies lead us in choosing therapies.
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FAQ
How many episodes does Future Pulse Cardiology have?
Future Pulse Cardiology currently has 21 episodes available.
What topics does Future Pulse Cardiology cover?
The podcast is about Life Sciences, Health & Fitness, Cardiology, Medicine, Podcasts and Science.
What is the most popular episode on Future Pulse Cardiology?
The episode title 'Diabetes and Cardiovascular Disease, SGLT2 inhibitors and GLP1 receptor agonists with Dr. Peter Toth' is the most popular.
What is the average episode length on Future Pulse Cardiology?
The average episode length on Future Pulse Cardiology is 30 minutes.
How often are episodes of Future Pulse Cardiology released?
Episodes of Future Pulse Cardiology are typically released every 18 days.
When was the first episode of Future Pulse Cardiology?
The first episode of Future Pulse Cardiology was released on Mar 7, 2022.
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