FoundMyFitness - #055 COVID-19 Q&A #2 - Antibody-Dependent Enhancement, Cross-Immunity, Immunity Duration & More

#055 COVID-19 Q&A #2 - Antibody-Dependent Enhancement, Cross-Immunity, Immunity Duration & More

06/10/20 • 55 min

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This is a continuation of the last episode where Dr. Patrick took questions from newsletter subscribers around the ongoing pandemic and tried to add value by talking about some of the recent research, among other things.

In this episode, you'll discover:

(00:00) Introduction
(04:06) Data surrounding SARS-CoV-2 duration
(06:30) SARS-CoV-2 and long-lasting immunity
(11:27) Genetic causes of immune variation
(14:27) Previous viral exposure and cross-immunity to SARS-CoV-2
(18:57) Antibody-dependent enhancement and SARS-CoV-2 relevance
(21:50) Sleep deprivation impairs immunity & vaccine efficacy
(23:42) Microbiome composition and immune function
(28:22) The differential effects of exercise intensity and duration on immune regulation
(34:10) Micronutrient inadequacies promote immune dysregulation
(46:32) Effects of sex and age in immune regulation
(48:59) Controversy surrounding hypertension drugs such as ACE inhibitors and COVID-19
(52:28) ARDS and long-term lung damage

If you’re interested in learning more, you can read the full show notes here.

Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

In this episode, you'll discover:

(00:00) Introduction
(04:06) Data surrounding SARS-CoV-2 duration
(06:30) SARS-CoV-2 and long-lasting immunity
(11:27) Genetic causes of immune variation
(14:27) Previous viral exposure and cross-immunity to SARS-CoV-2
(18:57) Antibody-dependent enhancement and SARS-CoV-2 relevance
(21:50) Sleep deprivation impairs immunity & vaccine efficacy
(23:42) Microbiome composition and immune function
(28:22) The differential effects of exercise intensity and duration on immune regulation
(34:10) Micronutrient inadequacies promote immune dysregulation
(46:32) Effects of sex and age in immune regulation
(48:59) Controversy surrounding hypertension drugs such as ACE inhibitors and COVID-19
(52:28) ARDS and long-term lung damage

If you’re interested in learning more, you can read the full show notes here.

Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Previous Episode

Vitamin C: Oral vs. Intravenous, Immune Effects, Cancer, Exercise Adaptation & More

In this episode, Dr. Rhonda Patrick discuss all things vitamin C. This episode covers oral bioavailability, intravenous vitamin C bioavailability, immune cell function, common cold and other viral infections, lung function, sepsis, pneumonia, inflammation, intravenous vitamin C and cancer, role in exercise, safety concerns, and so, so much more!

Episode Timeline (abridged)

00:07:33 - Background on vitamin C
00:17:09 - Bioavailability of vitamin C [including dosing frequency]
00:22:53 - Vitamin C in the context of the common cold
00:28:09 - Vitamin C and lung function
00:35:54 - Vitamin C in the context of exercise [includes discussion of blunting of exercise adaptation]
00:45:51 - Vitamin C and fatty acid oxidation, including relevance in obesity
00:48:44 - Vitamin C and the brain
00:51:15 - Intravenous Vitamin C and its use for the treatment of certain kinds of infection
00:55:33 - Intravenous Vitamin C and cancer
00:57:40 - Effect of Vitamin C on fertility and reproduction
00:58:36 - Intravenous vitamin C and cardiovascular health
01:00:42 - Vitamin C and inflammation
01:02:38 - Vitamin C’s mechanisms of action
01:08:34 - Intravenous and Oral vitamin C safety
01:10:20 - Vitamin C intake and kidney stone risk
01:13:57 - Conclusions

Get the full timeline, show summary, and all references for this episode by clicking here.

View our new 28-page vitamin C overview article with over 190 references by clicking here.

Premium membership: Members enjoy extra science emails twice per month, my monthly Question & Answer sessions, and a whole lot more. Support the show and get cool perks, that's the bottom line. Click here to learn more about premium membership.

Next Episode

#056 The Biology of Breast Milk

This episode aims to be the most comprehensive video compendium on the biology of breast milk ever recorded.

In this episode, you'll discover:

(00:00) Introduction
(07:11) Breast milk production and composition
(09:59) Human milk oligosaccharides help establish the infant gut microbiome
(16:32) Omega-3s in breast milk boost brain development
(18:15) Vitamins and minerals in breast milk
(22:05) Breast milk stem cells and multi-organ microchimerism
(22:54) Harmful substances transferred to infants via breast milk
(28:05) Breastfeeding boosts the infant's immune system
(31:17) Effects on intelligence
(34:36) Breastfeeding as a benefit to maternal health

If you’re interested in learning more, you can read the full show notes here.

Join over 300,000 people and get the latest distilled information on the biology of breast milk straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

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