How Toxins, Infections, And Gut Permeability Are Driving Our Epidemic Of Autoimmune Disease With Dr. Akil Palanisamy

04/13/23 • 145 min

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This episode is brought to you by Cozy Earth, BiOptimizers Magnesium Breakthrough, and Levels.

Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Akil Palanisamy to discuss why there’s been such an explosion in autoimmune disease and how certain insults in our modern-day society—like heavy metals, pesticides, poor diet, and chronic stress—could be to blame.

Dr. Akil is a renowned Integrative Medicine practitioner who combines conventional medicine with holistic approaches like Functional Medicine and Ayurveda. He is a Harvard graduate and received his MD from the University of California, San Francisco. Dr. Akil completed his residency training at Stanford University and a fellowship in Integrative Medicine with Dr. Andrew Weil at the University of Arizona. He has authored two books, The Paleovedic Diet and The TIGER Protocol which is set to be released on May 9th.

In this episode, Dhru and Dr. Akil dive into:

-The recent explosion in autoimmune disease (2:26)

-Top toxins that contribute to autoimmunity (6:26)

-How to combat toxin exposure using lifestyle (22:12)

-Conventional treatments for autoimmune disease (34:08)

-Why autoimmune conditions develop (39:23)

-Case example of people at high risk for autoimmunity (1:11:00)

-Dr. Akil’s two-phase diet recommendations for autoimmune disease (1:21:30)

-Blood tests and symptoms to detect early stages of autoimmunity (1:32:33)

-Foods central to repairing the gut (1:37:22)

-The carnivore diet for autoimmunity explained (1:48:36)

-Ancient Ayurvedic principles we can apply to our modern lifestyle (2:01:33)

-The importance of rest and mindset in autoimmunity (2:13:46)

Also mentioned in this episode:

-Dr. Akil’s clinic, Sutter Health

-The Paleovedic Diet

-Preorder Dr. Akil’s new book, The TIGER Protocol here.

For more on Dr. Akil Palanisamy, check out his website, doctorakil.com.

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This episode is brought to you by Cozy Earth, BiOptimizers Magnesium Breakthrough, and Levels.

In this episode, Dhru and Dr. Akil dive into:

-The recent explosion in autoimmune disease (2:26)

-Top toxins that contribute to autoimmunity (6:26)

-How to combat toxin exposure using lifestyle (22:12)

-Conventional treatments for autoimmune disease (34:08)

-Why autoimmune conditions develop (39:23)

-Case example of people at high risk for autoimmunity (1:11:00)

-Dr. Akil’s two-phase diet recommendations for autoimmune disease (1:21:30)

-Blood tests and symptoms to detect early stages of autoimmunity (1:32:33)

-Foods central to repairing the gut (1:37:22)

-The carnivore diet for autoimmunity explained (1:48:36)

-Ancient Ayurvedic principles we can apply to our modern lifestyle (2:01:33)

-The importance of rest and mindset in autoimmunity (2:13:46)

Also mentioned in this episode:

-Dr. Akil’s clinic, Sutter Health

-The Paleovedic Diet

-Preorder Dr. Akil’s new book, The TIGER Protocol here.

For more on Dr. Akil Palanisamy, check out his website, doctorakil.com.

Cozy Earth are the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code DHRU.

Hosted on Acast. See acast.com/privacy for more information.

Learn more about your ad choices. Visit megaphone.fm/adchoices

Previous Episode

Groundbreaking Hypothesis Identifies The Biggest Driver Of Alzheimer's Disease with Dr. Richard Johnson

This episode is brought to you by Birch Mattress by Helix and InsideTracker.

This week on The Dhru Purohit Podcast, Dhru sits down with Dr. Richard Johnson to discuss his revolutionary new hypothesis on the link between fructose consumption and Alzheimer’s disease. Dhru and Dr. Johnson discuss the evolutionary mechanism behind fructose metabolism, insulin resistance, and weight gain that has completely backfired today due to its overconsumption.

Dr. Richard Johnson is a professor of medicine at the University of Colorado Denver and has been a practicing physician and clinical scientist for over 25 years. He is internationally recognized for his seminal work on the role of fructose in obesity, diabetes, and now, Alzheimer’s disease. His work also highlights the fundamental role of uric acid (which is generated during fructose metabolism) in metabolic syndrome. He is the author of The Fat Switch and his newest bestselling book, Nature Wants Us to Be Fat.

In this episode Dhru and Dr. Johnson dive into:

-Dr. Johnson’s new hypothesis on the relationship between Alzheimer’s and fructose consumption (3:06)

-The origins of Alzheimer’s (what’s going on in the brain) (14:00)

-How modern-day life has hijacked our genetics to make us fat (23:08)

-How fructose impacts mitochondrial function (35:22)

-Why the body converts glucose to fructose (50:00)

-The relationship between salt, dehydration, and fructose production (1:03:03)

-How fructose makes us crave more sugar (1:09:23)

-Fructose and Alzheimer’s disease (1:11:46)

-The importance of strength training for glycemic control and Alzheimer’s prevention (1:30:53)

-Sources of fructose in our ancestral diet (1:36:00)

-The role of salt and dehydration in obesity (1:46:17)

-Hidden “healthy” sources of fructose in the diet (1:58:57)

-High-glycemic foods to minimize in the diet (2:00:03)

-Umami foods and uric acid (2:07:55)

-Dr. Johnson’s thoughts on Saturated fat (2:12:53)

Also mentioned in this episode:

-The Fat Gene

-Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?

-Study Suggests Fructose Could Drive Alzheimer's Disease (study press release)

-Nature Wants Us to Be Fat by Dr. Richard Johnson

-The End of Alzheimer's Program by Dr. Dale Bredesen

-Drop Acid by Dr. David Perlmutter

Birch Mattress by Helix is made out of organic latex, organic cotton, New Zealand wool, and American steel springs. To get 20% off your Birch Living mattress, head over to birchliving.com/dhru today.

InsideTracker provides detailed nutrition and lifestyle guidance based on your individual needs. Right now, they’re offering my podcast community 20% off. Just go to insidetracker.com/DHRU to get your discount and try it out for yourself.

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Next Episode

4 Powerful Hacks To Help You Cut Cravings And Get Your Energy Back With The Glucose Goddess Jessie Inchauspé

This episode is brought to you by WHOOP, InsideTracker, and BON CHARGE.

Today on The Dhru Purohit Podcast, Dhru sits down with Jessie Inchauspé—but you may know her by her wildly popular Instagram account, Glucose Goddess. In this episode, Jessie shares her revolutionary approach to balancing blood sugar and how to implement it while still having the freedom to mindfully indulge in the foods we love.

Jessie Inchauspé is on a mission to translate cutting-edge science into easy tips to help people improve their physical and mental health. She’s the founder of Glucose Goddess, where she teaches life-changing food habits to hundreds of thousands of people. She holds a bachelor of science degree in mathematics from King's College London and a master of science degree in biochemistry from Georgetown University. In her first book, Glucose Revolution, Jessie shares her startling discovery about the essential role of blood sugar in every aspect of our lives, from cravings to fertility, and the surprising hacks to optimize it while still eating the foods we love. Jessie’s newest book, The Glucose Goddess Method, explains how to put her glucose hacks into action and is set to be released on May 2, 2023.

In this episode, Dhru and Jessie dive into:

-Why we should care about glucose (2:31)

-Symptoms of glucose imbalances (4:03)

-Common sources of glucose spikes (14:33)

-Factors that affect glucose besides food (23:16)

-Have a savory breakfast over a sweet one (31:57)

-Movement for blood glucose control (40:52)

-How to use vinegar to hack your blood glucose (53:02)

-Strength training and muscle mass for better blood sugar control (1:07:03)

-The link between low blood sugar and panic attacks (1:16:53)

-The veggie starter to curb glucose spikes (1:21:20)

-Jessie’s philosophy about dessert (1:32:36)

Also mentioned in this episode:

-Preorder Jessie’s new book, The Glucose Goddess Method here.

-The science behind Glucose Goddess

-Could This Simple Hack Reduce Anxiety and Panic Attacks? (episode 194 with Dr. Kristen Allott)

For more on Jessie, follow her on Instagram @glucosegoddess, or through her website, glucosegoddess.com.

WHOOP is a personalized digital fitness tracker and health coaching platform that monitors your physiology 24/7 and provides personalized recommendations based on what your body needs. To get yours, go to join.whoop.com and get 15% off your membership with code DHRU15.

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