Alzheimer’s of the heart

05/05/23 • 43 min

Welcome to this episode of Deep Medicine, with your Host Alexander Gray: the Chief Medical Officer of IDEA Pharma. Alex has been joined by Marie Schroeder, who is a Senior Associate at Novo Seeds (https://novoholdings.dk/novo-seeds/). When this episode was recorded, she was a Principal Scientist at Novo Nordisk in Copenhagen, specializing in heart failure. Marie has spent a significant component of her career examining the role of amyloid in the pathogenesis of cardiomyopathy and is now involved in development programmes for assets aimed at treating patients with hereditary and acquired cardiac amyloidosis, as well as other trials examining cytokine blockade for the management of cardio-renal disease. Alex had a chance to discuss the parallels – and differences – between CNS and cardiac amyloid disease, from both pathologic and therapeutic perspectives.

You can find out more about Dr Schroeder and her work here:

https://www.novonordisk.com/careers/career-areas/research-and-development/cvd-researchers.html

You can find out more about Dr Schroeder and her work here:

https://www.novonordisk.com/careers/career-areas/research-and-development/cvd-researchers.html

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Deep Medicine | Avoiding the needle: how new imaging techniques are transforming prostate cancer detection

You can find out more about Professor Emberton and his work here: https://iris.ucl.ac.uk/iris/browse/profile?upi=MEMBE52

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Deep Medicine | Childhood trauma and the development of adult affective disorders: correlation or causation?

Welcome to this episode of Deep Medicine, with your Host Alexander Gray: the Chief Medical Officer of IDEA Pharma. Alex has been joined by Erika Kuzminskaitė, a Doctoral Researcher at the Department of Psychiatry, Amsterdam UMC, Vrije University, Amsterdam Public Health and Amsterdam Neuroscience Research Institutes (https://research.vumc.nl/en/persons/erika-kuzminskaite). Erika has been heavily involved with the Netherlands Study of Depression and Anxiety (NESDA), an ongoing longitudinal cohort study examining the course and consequences of depressive and anxiety disorders in a cohort with a current or remitted depressive and/or anxiety disorder, and a healthy control group. Alex discussed the complex relationships between different types of childhood trauma and adult affective disorders, and what is known about the neurobiological impact of childhood trauma, and how this might explain the development of adult mental health disorders.

You can find out more about Erika and her work here:

https://research.vumc.nl/en/persons/erika-kuzminskaite

1. Penninx BW et al. Int J Methods Psychiatry Res 2008; 17: 121–40