Daily Value
Dr. William Wallace
Daily Value is a podcast that takes a deep dive into essential nutrients and dietary practices that fuel our bodies and minds. Hosted by Dr. William Wallace, a leading product developer in the Natural Health Product industry and a dedicated educator in health and nutrition, this show is your go-to resource for understanding the science behind the vitamins, minerals, and supplements that influence human health.
Each short, digestible episode unpacks the latest scientific findings, protocols, and insights into how specific nutrients contribute to overall well-being. Whether you're a health professional, nutrition enthusiast, or just curious about how what you consume affects your health, Daily Value offers evidence-based discussions to help you make informed decisions for a healthier life.
Join Dr. Wallace as he shares his expertise, developed from years of experience in product development and nutrition science, to advance your knowledge and awareness of dietary interventions for optimal health. Get your daily value and add meaningful insights to your day, one episode at a time.
DISCLAIMER: William Wallace holds a Ph.D. He is not a medical doctor. Content generated for this channel is strictly for educational purposes and does not constitute medical advice. The content of this channel is not meant to substitute for standard medical advice, diagnosis, or treatment. Please consult with your primary healthcare practitioner before beginning any nutrition-, or supplement-based protocols. This is especially important if you are under the age of 18, undergoing treatment for a medical condition, or if you are pregnant or nursing.
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Top 10 Daily Value Episodes
Goodpods has curated a list of the 10 best Daily Value episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Daily Value for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Daily Value episode by adding your comments to the episode page.
How Ashwagandha Might Elevate Your VO2 Max
Daily Value
09/11/24 • 7 min
In the latest episode of Daily Value, we explore new research on Ashwagandha’s potential to enhance physical performance, focusing on its ability to increase VO2 max, based on a recent eight-week randomized controlled trial (PMID: 38988644). Traditionally known for stress reduction, Ashwagandha is emerging as a interesting supplement with potential for improving endurance and aiding recovery.
Talking Points:
- Can Ashwagandha help improve VO2 max and overall endurance?
- Theoretical mechanisms involving influencing the hypothalamic-pituitary-adrenal (HPA) axis, cortisol responses and hemoglobin.
- Dosing strategies: how a specific amount of Ashwagandha daily, with specific standardizations, might lead to gains in VO2 max and endurance (when combined with the right training program).
I break down some of the science behind these findings and whether Ashwagandha supplementation makes sense to add in your fitness routine
09/16/24 • 8 min
In today’s episode of Daily Value, we look at new research that highlights how Nicotinamide Riboside supplementation, for the first time, was shown to elevate NAD+ levels in the brain, with potential implications for cognitive health and longevity.
Episode Talking Points:
*Mechanisms through which NAD+ supports brain health, including its role in DNA repair, energy production, and neuroprotection.
*Key findings from a recent study showing a 16% average increase in cerebral NAD+ levels just hours after NR supplementation.
*The potential for NR supplementation to help protect against age-related cognitive slowdown and support overall brain health.
https://onlinelibrary.wiley.com/doi/10.1002/mrm.30227#:~:text=Another study assessed the effects,to a 30-day placebo
From Scurvy to Success: How Vitamins Revolutionized Modern Nutrition Science (The Vitamins Part 1)
Daily Value
09/27/24 • 14 min
In today’s episode of Daily Value, we begin a special series called “The Vitamins,” where we’ll dive deep into the discovery, functions, and importance of vitamins in human health. This first episode lays the groundwork by exploring the history of vitamin discovery, from the 19th-century realization that certain diseases were tied to diet, to the revolutionary concept of vitamins and their role in preventing specific deficiency diseases. We’ll also cover key definitions, the defined physiological functions of vitamins, thereby allowing us to better understand how they impact our daily health.
Episode Talking Points:
- The historical context of vitamin discovery and how it changed the course of nutrition science.
- Defining vitamins: their essential role, how they differ from macronutrients, and the five-part definition of what makes a vitamin.
- The functions of vitamins in the body, from acting as coenzymes and antioxidants to influencing gene transcription.
Tune in to gain a deeper understanding of vitamins and their critical role in supporting overall health.
10/04/24 • 9 min
In today’s episode of Daily Value, we explore the connection between B vitamins, and immune system, focusing on how dietary fiber fuels this relationship. While it’s well-known that fiber is essential for digestive health, new research (PMID: 39307855 - rodent data) demonstrates that it plays an even more complex role—boosting the available pool of B vitamins produced by gut bacteria, which in turn improved immune function. This episode will look at the interplay between gut bacteria, fiber, and the immune system, and how this trio could affect health outcomes.
Episode Talking Points:
*How dietary fiber influences the gut microbiota’s ability to produce B vitamins and increase the available pool of bacteria-produced B vitamins.
*The gut microbiome’s role in maintaining a healthy immune system through vitamin production, and how fiber deprivation can upset this balance.
*Research on fiber’s impact on gut health and immunity, revealing that fiber can promote anti-inflammatory immune cells and improve immune regulation.
These insights could redefine the way you think about fiber and nutrition.
https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-024-01898-7
01/08/25 • 8 min
In this episode of Daily Value, we examine the latest research on wine consumption and its relationship to cardiovascular health. Leveraging urinary tartaric acid as an objective biomarker, a recent study (PMID: 39689849) published in the European Heart Journal provides interesting evidence of a J-shaped association between wine intake and cardiovascular outcomes.
Discussion Points:
- Biomarkers and Bias: The role of urinary tartaric acid in providing a reliable objective measure of wine consumption, avoiding the recall and social desirability biases inherent in self-reported dietary studies.
- Mechanisms of Action: The potential cardioprotective effects light to moderate wine intake (are they real?)
- Dose-Dependent Effects: Insights into the J-shaped curve, revealing cardiovascular benefits with light-to-moderate consumption and increased risk with heavier intake.
https://pubmed.ncbi.nlm.nih.gov/39689849/
01/29/25 • 8 min
In this episode of Daily Value, we look at how extra virgin olive oil and its polyphenols—including hydroxytyrosol—could impact your health and longevity. Referencing evidence from the Moli-Sani Study and other meta-analyses (PMID: 38704428), we uncover how these bioactives are suggested to reduce risks for cancer, cardiovascular disease, and all-cause mortality.
Discussion Points:
- Bioactive Compounds: How hydroxytyrosol prevents LDL oxidation and reduces inflammation, key mechanisms for cardiovascular protection.
- Landmark Studies: The Moli-Sani cohort found a 28% reduction in cancer deaths with a certain threshold of olive oil, while meta-analyses confirm a 16% lower cardiovascular risk with similar amounts of olive oil.
- Practical Takeaways: Why cold-pressed extra virgin olive oil is essential for these benefits and how just 3 tablespoons daily could support health outcomes.
https://pubmed.ncbi.nlm.nih.gov/38704428/
02/17/25 • 9 min
In this episode of Daily Value, we look at the latest research on B vitamins and their in neuropsychiatric disorders. A newly published meta-analysis suggests a causal relationship between B vitamin deficiencies and neuropsychiatric disorders. We will break down the scientific findings on B6, B12, and folate, shedding light on their roles in conditions like Parkinson’s disease.
Discussion Points:
- How recent genetic studies support a causal link between B vitamin deficiencies and mental health conditions.
- The role of B vitamins in reducing neurotoxicity and slowing brain atrophy.
- How vitamin B12 may protect against dopamine neuron loss and disease progression.
- Evidence linking low B6 levels to neurotransmitter imbalances and schizophrenia risk.
- The impact of folate on one-carbon metabolism and its protective role in neurodegeneration.
https://pubmed.ncbi.nlm.nih.gov/26757190/
https://pubmed.ncbi.nlm.nih.gov/32257364/
https://pubmed.ncbi.nlm.nih.gov/30858560/
https://pubmed.ncbi.nlm.nih.gov/32424116/
https://pubmed.ncbi.nlm.nih.gov/33941768/
05/19/25 • 11 min
Debunking Myths: The safety and side effects of creatine supplementation. In this episode of Daily Value we look into the safety concerns surrounding creatine supplementation. Creatine, a well-researched dietary supplement known for its muscle-building and performance-enhancing benefits, has sparked numerous myths about its effects on kidneys, hair loss, and dehydration. We will evaluate recent studies and scientific evidence to address these myths.
Topics include creatine's impact on water retention, kidney function, and hair health. Tune in to discover the truth about one of the most studied and [possibly safest] supplements available.
00:00 Introduction: Creatine Myths
00:46 Dietary Intake and Muscle Storage
01:28 Creatine's Cognitive and Anti-Aging Benefits
02:10 Addressing Common Creatine Myths
03:05 Myth 1: Creatine and Water Retention
04:26 Myth 2: Creatine and Kidney Function
08:11 Myth 3: Creatine and Hair Loss
09:42 Comprehensive Safety Analysis
10:37 Conclusion: Is Creatine Safe
PMID: 31375416
PMID: 39778146
PMID: 40265319
PMID: 40198156
PMID: 39796530
The Nutrient Duo That Could Save Your Mind
Daily Value
05/26/25 • 8 min
In this episode of Daily Value, we look into the synergistic relationship between two nutrient classes in supporting brain health and mitigating cognitive decline. Drawing on evidence from past clinical evidence suggesting these two nutrient classes work in tandem to support brain function and health.
Discussion Points:
-Homocysteine’s role in disrupting fatty acid incorporation into cell membranes and amyloid-beta clearance.
-Findings from one study, where some 70-year-old participants experienced up to 30% reduction in brain atrophy.
-Practical strategies to optimize intake of these nutrients.
00:00 Introduction to Brain Health and Nutrition
01:06 Understanding Mild Cognitive Impairment
01:44 The Role of B Vitamins and Omega-3s
02:34 Mechanisms of One Carbon Metabolism
03:06 Impact of Homocysteine on Brain Health
04:12 Key Studies on Nutrient Synergy
07:05 Practical Dietary Recommendations
08:07 Conclusion and Final Thoughts
https://pubmed.ncbi.nlm.nih.gov/22260268/
https://pubmed.ncbi.nlm.nih.gov/29480200/
https://pubmed.ncbi.nlm.nih.gov/26757190/
Today's episode is a recap and "roundup" of research articles that were published in December 2023. Although we cannot take one single paper and make broad-sweeping claims, I do believe there are practical considerations and takeaways for each one of the papers that I chose for the episode.
The first paper tackles how lifestyle choices (even those of the father) might impact future generations. The authors of the study urge men to consider the potential shadow that paternal alcohol use has on future offspring. The research presents a compelling case for pre-conception alcohol abstinence, linking a father's drinking habits to potential birth defects due to sperm alterations. Moreover, I will discuss the surprising cognitive boosting effects of Lion's Mane mushroom in young people after one-time administration.
Next, I will go over the nuances of pain-relieving medication and pregnancy health, scrutinizing recent findings on acetaminophen use in the third trimester of pregnancy and childhood outcomes. From there I will shift gears to discuss a systematic review that outlines the benefits of glycine supplementation in healthy populations, highlighting its role in enhancing sleep quality and cognitive function, along with possible implications for aging research. Lastly, the conversation goes into advances in personalized nutrition. Specifically, how fiber might be differently affecting gut bacteria, and how those same bacteria matter for what fibers it is you consume.
Be sure to subscribe for future episodes covering specific nutrients and strategies for achieving optimal nutrient adequacy.
Papers cited in the podcast:
Paternal alcohol use: https://onlinelibrary.wiley.com/doi/10.1111/andr.13566
Lions mane: https://www.mdpi.com/2072-6643/15/22/4842
Acetaminophen use during pregnancy: https://www.nature.com/articles/s41390-023-02924-4
Glycine: https://link.springer.com/article/10.1007/s11357-023-00970-8
Fiber: https://pubmed.ncbi.nlm.nih.gov/37942526/
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FAQ
How many episodes does Daily Value have?
Daily Value currently has 55 episodes available.
What topics does Daily Value cover?
The podcast is about Health & Fitness, Nutrition, Alternative Health, Podcasts, Science and Health.
What is the most popular episode on Daily Value?
The episode title 'Unlocking Energy: The Essential Role of "the First Vitamin" Vitamin B1 (Thiamine)' is the most popular.
What is the average episode length on Daily Value?
The average episode length on Daily Value is 14 minutes.
How often are episodes of Daily Value released?
Episodes of Daily Value are typically released every 2 days.
When was the first episode of Daily Value?
The first episode of Daily Value was released on Jun 19, 2023.
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