
Ep. 106: On the Verge: Leaders in Bioscience Discuss the State of Vaccines and Treatments
11/10/20 • 48 min
George Yancopoulos
Co-founder and Chief Scientific Officer, Regeneron
Joseph Vinetz
Professor of Medicine, Yale University; Infectious Disease Physician
Tal Zaks
Chief Medical Officer, Moderna
“We're going to need vaccines to create as widespread herd immunity as we can, but we're also going to need drugs that are targeted against the virus that can provide immediate protection and also treat those who are already sick. So we have multiple clinical trials ongoing with our antibody cocktail, both for prophylaxis or prevention and also for treatment.” – George Yancopoulos, Regeneron
Three world-renowned bioscience leaders join Mike Milken and Prostate Cancer Foundation (PCF) chief science officer Howard Soule for a conversation on the state of the COVID-19 challenge, herd immunity, and unique approaches to developing safe and effective vaccines, antibodies, and other treatments. Recorded on August 29 as part of a PCF event, this conversation is especially notable as it describes the antibody cocktail that would later be administered to President Donald Trump after he contracted the virus.
Moderna’s Tal Zaks is optimistic that scientists are on the verge of a breakthrough that we’ll learn more about very soon. “In the coming months,” he tells Howard, “expect data from us and potentially some of the other vaccine companies that also have started phase 3 trials that will conclusively demonstrate that these vaccines can work. I hope all of them succeed because I don't think a single company can carry the weight of what's needed to protect all of us and all those who need it.”
George Yancopoulos
Co-founder and Chief Scientific Officer, Regeneron
Joseph Vinetz
Professor of Medicine, Yale University; Infectious Disease Physician
Tal Zaks
Chief Medical Officer, Moderna
“We're going to need vaccines to create as widespread herd immunity as we can, but we're also going to need drugs that are targeted against the virus that can provide immediate protection and also treat those who are already sick. So we have multiple clinical trials ongoing with our antibody cocktail, both for prophylaxis or prevention and also for treatment.” – George Yancopoulos, Regeneron
Three world-renowned bioscience leaders join Mike Milken and Prostate Cancer Foundation (PCF) chief science officer Howard Soule for a conversation on the state of the COVID-19 challenge, herd immunity, and unique approaches to developing safe and effective vaccines, antibodies, and other treatments. Recorded on August 29 as part of a PCF event, this conversation is especially notable as it describes the antibody cocktail that would later be administered to President Donald Trump after he contracted the virus.
Moderna’s Tal Zaks is optimistic that scientists are on the verge of a breakthrough that we’ll learn more about very soon. “In the coming months,” he tells Howard, “expect data from us and potentially some of the other vaccine companies that also have started phase 3 trials that will conclusively demonstrate that these vaccines can work. I hope all of them succeed because I don't think a single company can carry the weight of what's needed to protect all of us and all those who need it.”
Previous Episode

Ep. 105: Pioneering, with FOX’s Maria Bartiromo
“It goes back to opportunity and jobs.... Government can only do so much. The private sector needs to step up and ensure that they are creating opportunities for a broad swath of the population who don't have those opportunities.”
When Maria Bartiromo became the first journalist to report live from the floor New York Stock Exchange in 1995, she was well on her way to another honor: the first female journalist to be inducted into the Cable Hall of Fame. Throughout her career, the two-time Emmy Award winner has interviewed presidents, policymakers, and CEOs, but always with an ear for what her audience needs to know.
“I want to make sure to get from that person, the one thing that will resonate for broad, big groups of people,” she tells Mike. “Their words will impact people and they will perhaps move the needle on something like income inequality or something like giving that person the courage to stick their neck out and try something new.”
Next Episode

Ep. 107: Dealmaker, with Thoma Bravo’s Orlando Bravo
“There were a lot of hedge fund blogs out there saying software is going to get destroyed. ... And guess what happened? Our recurring revenue stream was really nearly untouched in a pandemic. Corporate customers paid their subscription software revenue, but they didn't pay rent. It was more stable than real estate.”
To this day, Orlando Bravo would rather have played Wimbledon than become the first Puerto Rican-born billionaire. As a teen, he was a top-40 junior player; as an adult, Bravo eventually co-founded Thoma Bravo, a private equity firm specializing exclusively on software deals. Forbes recently called him “Wall Street’s best dealmaker.” He may also be one of its most generous: In the aftermath of Hurricane Maria, Bravo chartered planes to Puerto Rico carrying $10,000,000 in essential goods and committed an additional $100,000,000 to foster entrepreneurship and economic development on the island.
As he tells Mike, “After the hurricane in Puerto Rico ... that was my personal moment in philanthropy where I understood for the first time that if I didn't do anything about it, nobody else was going to.”
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