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Choosing Science: Stories of Perseverance, Humanity, and Success - Mice as discovery driver or how to be small, but help achieve great things

Mice as discovery driver or how to be small, but help achieve great things

Choosing Science: Stories of Perseverance, Humanity, and Success

04/28/24 • 19 min

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Mice (17th century- current)
Some find them cute, some find them repulsive, and science finds them useful. Mice have been a model organism for a bit over a century and is by far the most used nowadays. Let’s find out what these little creatures did for scientific discoveries and learn cool facts about them at the same time.
Resources:

https://www.nature.com/articles/s41593-021-00849-x

https://www.labome.com/method/Laboratory-Mice-and-Rats.html

https://www.sciencedirect.com/science/article/pii/B9780128165737000067

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790571/

Cool facts: https://www.yourgenome.org/facts/why-use-the-mouse-in-research

Video: https://www.nytimes.com/2021/05/25/science/optogenetics-brain-social-behavior.html

Example failed animal trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964774/

Micronucleus test: https://en.wikipedia.org/wiki/Micronucleus_test

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04/28/24 • 19 min

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Choosing Science: Stories of Perseverance, Humanity, and Success - Mice as discovery driver or how to be small, but help achieve great things

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The Mouse as model organism

Some find them cute, some find them repulsive, and science finds them useful. Mice have been a model organism for a bit over a century and is by far the most used nowadays. Let’s find out what these little creatures did for scientific discoveries and learn cool facts about them at the same time.

First tho let’s understand what a model organism is actually. This term is used to describe non-human species in which scientists can model and research di

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