Cardiovascular Matters

In this episode of Cardiovascular Matters, Dr. Craig Walker and Terry Roberts delve into the groundbreaking treatment of renal denervation for patients struggling with uncontrolled hypertension and it has been approved by the FDA.
Hypertension is a prevalent and potentially life-threatening condition, often requiring a combination of medications to manage. However, for some individuals, even multiple medications fail to effectively control their blood pressure.
Enter renal denervation, a novel procedure that disrupts the nerves surrounding the kidney arteries, reducing the body's sympathetic nervous system activity and leading to a significant drop in blood pressure. Dr. Walker, an early investigator of this technology, shares his firsthand experiences and the remarkable results he has witnessed in his patients.
Listeners will gain a comprehensive understanding of the causes and consequences of hypertension, the limitations of traditional medication-based treatments, and the promising potential of renal denervation as a game-changing solution. This episode delves into the approval process, the different approaches to the procedure, and the impressive outcomes that have been observed, including patients being able to reduce or even discontinue their blood pressure medications altogether.
Whether you or a loved one are struggling with uncontrolled hypertension or simply want to stay informed about the latest advancements in cardiovascular care, this episode is a must-listen. Prepare to be enlightened and inspired by the potential of renal denervation to transform the lives of those battling this prevalent and dangerous condition.
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In this informative episode of the Cardiovascular Matters podcast, host Dr. Craig Walker sits down with his colleague Terry Roberts to discuss pulmonary embolisms (PEs) in comprehensive detail. PEs, which occur when blood clots travel to the lungs, are a serious cardiovascular condition that can quickly become life-threatening if not properly diagnosed and treated.

Dr. Walker begins by explaining what a PE is on a physiological level, noting how clots blocking blood flow in the lungs can strain the heart and prevent oxygenation of blood throughout the body. He discusses how PEs originate as clots elsewhere in the body, most commonly the legs, that break off and travel to the lungs. Depending on their size, PEs can range from causing minor breathing issues to sudden cardiac arrest.

The discussion then delves into risk factors for developing PEs. Genetic hypercoagulable conditions that cause easier clotting are highlighted, as are external risk factors like smoking, prolonged immobility, recent surgery or trauma, and certain cancers. Dr. Walker stresses the importance of prophylactic measures for at-risk patients, such as compression stockings and blood thinners.

Some key points:

• PEs are the second leading cause of death from cardiovascular disease and can be fatal if large clots block oxygen from circulating in the blood.
• Risk factors for PEs include hypercoagulability, injury, prolonged immobility, surgery, cancer and smoking.
• Symptoms include shortness of breath, arrhythmias, and potentially sudden death from large clots.
• Diagnosis involves imaging tests like CT scans to detect clots in the lungs.
• Traditional treatments include blood thinners like heparin to prevent further clotting.
• Newer options like thrombolytic drugs and thrombectomy devices can dissolve or remove clots quickly in severe cases.
• Emergency support like ECMO can oxygenate the blood while clots are addressed.

Turning to diagnosis, imaging tests like CT scans that can detect clots in the pulmonary arteries are outlined. Dr. Walker also notes newer diagnostic guidelines that help physicians determine the likelihood a patient is experiencing a PE. Traditional first-line treatments involving blood thinners are explained, along with their limitations in dissolving large clots.

The bulk of the conversation focuses on recent advances in PE treatment. Dr. Walker enthusiastically discusses thrombolytic drugs that break down clots, endovascular thrombectomy devices that physically remove clots, and emergency circulatory support like ECMO. He shares inspiring case studies of how these interventions have saved critically ill patients within minutes of their arrival. The risks of these procedures are also addressed.

Overall, this podcast episode is an invaluable resource for anyone seeking to learn more about pulmonary embolisms, from causes and symptoms to state-of-the-art diagnosis and life-saving therapies. Dr. Walker's expertise and passion for the topic shine through, making complex cardiovascular science easy to understand.
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Have you or a loved one struggled with painful, persistent venous ulcers? In this episode of Cardiovascular Matters, Dr. Craig Walker sheds light on venous disease - a common condition that often goes undiagnosed and untreated.

Dr. Walker's interest in venous issues began early in his career while working to open blocked arteries and access the heart. It was in wound healing centers that he noticed the majority of patients suffered from debilitating venous ulcers, not arterial issues. These ulcers could last decades, constantly weeping and requiring bandage changes day and night.

One key culprit is iliac vein compression - where the large veins in the abdomen become squeezed between the aorta and spine. Dr. Walker explains the anatomy and risk factors for compression, detailing how it raises venous pressures and predisposes people to ulcer formation. But for years, there were no effective treatments.

That changed with pioneering work by Dr. Raju using minimally invasive vein stenting. Dr. Walker was amazed by the rapid ulcer healing he saw in patients. Now newer stents and techniques have made the procedure even safer.

In this episode, Dr. Walker shares real case studies of patients with 20+ year ulcers that fully healed within months of stenting. He stresses the importance of evaluating for compression in anyone with longstanding ulcers or discolored legs. Tune in to learn more about diagnosis and new hope for patients suffering from this debilitating condition.
Here are the key points discussed in the podcast episode:

• Dr. Walker's career path led him to recognize the prevalence of venous disease issues over arterial problems when working in wound healing centers.
• Venous ulcers are one of the most common problems treated, often lasting decades and severely impacting quality of life.
• Iliac vein compression, where the iliac veins in the abdomen become squeezed, is a major underlying cause of venous hypertension and ulcer formation.
• Risk factors for compression include family history, obesity, recurrent leg clots, and discolored skin below the knees.
• Non-invasive testing like ultrasound has limitations - intravascular ultrasound placed in the vein is the gold standard diagnostic test.
• Pioneering work by Dr. Raju in the 1990s demonstrated minimally invasive vein stenting could effectively decompress veins and rapidly heal ulcers.
• Newer stents, balloons and techniques have made the outpatient stenting procedure even safer and more successful.
• Case studies showed ulcers persisting over 20 years could fully heal within 6-8 weeks post-stenting.
• Anyone with longstanding ulcers or symptoms should be evaluated for possible iliac vein compression.

Dr. Craig Walker and Terry Roberts discuss varicose veins and other venous disorders on this episode of Cardiovascular Matters. They delve deeper into obstructive venous disorders like iliac vein compression syndrome, also known as May-Thurner syndrome
In this episode, Dr. Walker sits down with host Terry Roberts to explore causes of venous obstruction beyond simple varicose veins. They discuss conditions like first rib syndrome that can compress veins as well as how cancer and infections can indirectly cause obstructions. However, Dr. Walker focuses particular attention on iliac vein compression syndrome, otherwise known as May-Thurner syndrome. He explains in detail how the iliac artery can compress and reduce blood flow through the iliac vein at the spine. Left untreated, this puts patients at higher risk of dangerous blood clots and prevents healing of chronic venous ulcers.
Listeners learn the importance of considering iliac vein compression when evaluating patients with severe leg swelling, ulcers, or large clots found predominantly on one side. Dr. Walker outlines the diagnostic process which may involve ultrasound, venography, and intravascular ultrasound to visualize compression sites. He also shares how balloon angioplasty and stent placement have transformed the lives of patients who suffered for decades before receiving proper treatment.
Beyond individual patient stories, the episode offers insights into symptoms of venous obstruction and how it can impact exercise capacity and hemodialysis access. Dr. Walker contrasts treating venous strictures to arterial blockages as well. The discussion wraps by emphasizing this common problem is frequently overlooked and how advanced endovascular techniques now offer hope.
***------------- Key points discussed -------------***

• Dr. Walker discusses varicose veins and delves deeper into obstructive venous disorders like iliac vein compression syndrome (May-Thurner syndrome).
• Conditions beyond varicose veins that can cause venous obstructions include first rib syndrome, cancer, infections.
• Iliac vein compression occurs when the iliac artery crosses and compresses the iliac vein against the spine, increasing risk of clots and preventing ulcer healing.
• Diagnosis involves ultrasound initially but may require venography and intravascular ultrasound to visualize compression sites.
• Treatment is usually balloon angioplasty and stent placement to hold the vein open.
• Stories shared of life-changing impacts proper venous treatment has had for long-term patients.
• Symptoms discussed include leg swelling and shortness of breath.
• Venous disease importance for hemodialysis patients is covered.
• Venous strictures are harder to treat than arterial blockages.
• Advanced stents are now available to treat various venous obstructions

Listeners learn this common cardiovascular problem is often underdiagnosed and underestimated. Identifying and addressing venous issues can transform a patient's quality of life. This episode provides valuable information for those experiencing related symptoms.
We hope you will take the time to listen to this informative podcast. Please feel free to share it with others who may benefit from a deeper understanding of venous disorders. As always, thank you for your ongoing support of Cardiovascular Matters.

In the premiere episode of Cardiovascular Matters, hosts Dr. Craig Walker and Terry Roberts delve into a comprehensive explanation of varicose veins and venous insufficiency.

Dr. Walker begins by providing context on the prevalence of venous disease, affecting over half of Americans. However, it is often misunderstood due to a lack of public education. He underscores that veins play a critical yet underappreciated role in circulating blood back to the heart for oxygenation.

A detailed description of venous anatomy and physiology is given. Valves in the veins help blood flow against gravity but can become dysfunctional, causing venous insufficiency. Signs like leg swelling and spider veins appear as a result of increased pressures within the veins.

Risk factors for developing insufficiency are explored. Jobs requiring long periods of standing, multiple pregnancies stretching veins, family history and weight all influence one's risk. Listeners gain valuable insights into what may predispose them.

Treatment approaches are separated into conservative and interventional options. Lifestyle changes like exercise and compression are first-line therapies if symptoms are mild. But more invasive procedures are needed for severe cases using laser, radiofrequency, foam and devices.

Terry asks thoughtful questions that provide opportunities for further explanation. Dr. Walker clarifies spider veins often signify deeper issues, and stresses the importance of upright ultrasound exams for accurate diagnosis.

This in-depth pilot episode leaves no stone unturned in the discussion of varicose veins. Listeners walk away with a comprehensive understanding of causes, signs, risk factors and a full spectrum of treatment strategies - both non-invasive and cutting-edge procedures. It establishes Cardiovascular Matters as must-listen resource for all seeking cardiovascular health insights.