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While the trend toward CB1 inhibition for obesity took a small hit with the release of Novo Nordisk's small molecule oral cannabinoid receptor (CB1) inverse agonist monlunabant last month, Skye Bioscience Chairman and CEO Punit Dhillon is shaking it off. He's confident that his company's antibody-based approach to CB1 inhibition will make a moot point of the neuropsychiatric side effects that put a damper on Novo's data. On this episode of the Business of Biotech, we're digging into the uber-hot business of weight loss therapeutics and going deep with Dhillon on why Skye's blood/brain barrier-obeying antibody might turn the GLP-1 and small molecule approaches to obesity on their ears. Over the course of the conversation, we explore the ins-and-outs of the business of metabolic health, a space that's churning out one blockbuster after another.
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10/21/24 • 62 min
Business Of Biotech - Obesity Tx End-Around With Skye Bioscience's Punit Dhillon
Transcript
GLP-1 inhibitors have blown the obesity therapeutics market wide open , and what a crazy market it is . On one side of the continuum , there's the billions of dollars being spent by the vanity crowd people looking for a quick weight loss bump in advance of a wedding or a vacation
Matt Pillarand on the other end of the continuum are patients
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