Biomes

Fecal transplants are one of the hottest, if not stomach-curling, topics in the field of the microbiome at the moment. They are extremely successful treatments for recurrent C. Diff infection. In this episode I speak with Dr. Majdi Osman who is the Clinical Programme Director of OpenBiome, a non-profit stool bank whom screen, store and distribute stool samples to hospitals all around the US for fecal transplants. We discuss the background of fecal transplants, the day-to-day difficulties of running a stool-bank and the future of this nauseating treatment for other diseases.

In this episode of Biomes, I speak with Professor Gregor Reid of the the University of Western Ontario and the Lawson Health Research Institute, one of the foremost researchers on probiotics. We discuss his research into UTIs, preterm birth, probiotic controversies and the future of beneficial microbes to fight disease.

Have you ever had a gut feeling? Or butterflies in your stomach? Fascinating evidence now shows us that our intestines and brains and intricately linked through a number of physical and biochemical pathways and that our gut microbes are critical to these interactions.

In this episode of Biomes, I speak with Professor Ted Dinan from University College Cork, one of the pioneers in the field of the gut-brain axis. We talk about the link between stress and infection, the latest knowledge around the vagus nerve and what diet he thinks may be key to gut-brain health.

Enjoy!

Infectious diseases have largely been replaced by chronic diseases such as diabetes, heart disease and cancer in the Western world. However, the COVID-19 pandemic has shown us that humans are still at significant risk from microbial-diseases. In this episode, Dr. Ruairi Robertson speaks with Prof. Brett Finlay from University of British Columbia, one of the world’s leading experts on infectious diseases. Prof. Finlay discusses his career studying infectious microbes and how this led him to shift focus to all of the other microbes in our body. He discusses the influence of the gut microbiome on infection susceptibility, fulfilling Koch’s postulates for the gut microbiome and the influence of early life gut microbes on ‘modern plagues’ such as asthma and allergies.

Prof. Finlay is one of the scientific co-founders of Microbiome Insights along with Dr. Bill Mohn. Between them, they have published more than 600 peer reviewed papers and they provide key scientific guidance to the Microbiome Insights team. Find out more at www.microbiomeinsights.com.

When you hear the phrase ‘gut microbiome’, you most often think about bacteria. However, a huge proportion of your intestinal microbes are viruses, archaea and fungi. These other microbes however, have been studied in much less detail and we know less about what they are doing to your body. In this episode, Dr. Ruairi Robertson speaks with Dr. Marie Claire Arrietta from University of Calgary, a leading researcher on fungal microbiomes. She discusses how gut fungi interact with the immune system, myths about Candida and how gut fungi may affect children’s lung health.

Microbiome Insights provide services to assess the fungal microbiome using ITS2 sequencing. Find out more at www.microbiomeinsights.com