Dr. Shayn Peirce-Cottler on Alzheimer's and Diabetes, How Disease Impacts the Smallest Blood Vessels
09/11/24 • 51 min
Microvessels are a crucial part of our body’s circulatory system. They're responsible for delivering the oxygen and nutrients to every cell in your body and are often devastated by diseases like Diabetes and Alzheimer's. Dr. Peirce-Cottler develops computational models and combines them with wet lab experiments to study how tissues heal after injury and to develop therapies for inducing tissue regeneration.
Love this podcast? Write to us with ideas, feedback, and guest recommendations at [email protected]
Dr. Shayn Peirce-Cottler the is Harrison Distinguished Teaching Professor and Chair of Biomedical Engineering, with secondary appointments in the Department of Ophthalmology and Department of Plastic Surgery at the University of Virginia (UVA). In this episode of Biomedical Frontiers, we dive into the history and future of microvascular research, the observed connection between Alzheimer's and diabetes, and the future healthcare applications of computational modeling.
Dr. Peirce-Cottler received Bachelor’s of Science degrees in Biomedical Engineering and Engineering Mechanics from The Johns Hopkins University and her Ph.D. in the Department of Biomedical Engineering at the University of Virginia. She has published over 125 peer reviewed papers and book chapters, is a fellow in both the American Institute for Medical and Biological Engineering College of Fellows (AIMBE) and the Biomedical Engineering Society (BMES). She was awarded the UVA School of Medicine’s Robert H. Kadner Award for Excellence in Graduate Teaching and Mentoring. Her courses in cell and molecular physiology and computational systems bioengineering are foundational to the BME undergraduate and graduate studies at UVA.
Follow Dr. Shayn Peirce-Cottler on Social Media
LinkedIn: https://www.linkedin.com/in/shayn-peirce-cottler-a70993/
Check out Dr. Peirce-Cottler’s work: https://www.peircecottlerlab.com/
Recent publications from Shayn’s lab: https://www.peircecottlerlab.com/publications
Check out Dr. Shannon Barker's page: https://engineering.virginia.edu/faculty/shannon-barker
Read about combining synthetic biology, computational modeling, and machine learning to design and build tissues: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1010701
Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com
Executive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA
Senior Producer: Hannah Moore, Associate Director, UVA Coulter
Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com
Produced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research
Microvessels are a crucial part of our body’s circulatory system. They're responsible for delivering the oxygen and nutrients to every cell in your body and are often devastated by diseases like Diabetes and Alzheimer's. Dr. Peirce-Cottler develops computational models and combines them with wet lab experiments to study how tissues heal after injury and to develop therapies for inducing tissue regeneration.
Love this podcast? Write to us with ideas, feedback, and guest recommendations at [email protected]
Dr. Shayn Peirce-Cottler the is Harrison Distinguished Teaching Professor and Chair of Biomedical Engineering, with secondary appointments in the Department of Ophthalmology and Department of Plastic Surgery at the University of Virginia (UVA). In this episode of Biomedical Frontiers, we dive into the history and future of microvascular research, the observed connection between Alzheimer's and diabetes, and the future healthcare applications of computational modeling.
Dr. Peirce-Cottler received Bachelor’s of Science degrees in Biomedical Engineering and Engineering Mechanics from The Johns Hopkins University and her Ph.D. in the Department of Biomedical Engineering at the University of Virginia. She has published over 125 peer reviewed papers and book chapters, is a fellow in both the American Institute for Medical and Biological Engineering College of Fellows (AIMBE) and the Biomedical Engineering Society (BMES). She was awarded the UVA School of Medicine’s Robert H. Kadner Award for Excellence in Graduate Teaching and Mentoring. Her courses in cell and molecular physiology and computational systems bioengineering are foundational to the BME undergraduate and graduate studies at UVA.
Follow Dr. Shayn Peirce-Cottler on Social Media
LinkedIn: https://www.linkedin.com/in/shayn-peirce-cottler-a70993/
Check out Dr. Peirce-Cottler’s work: https://www.peircecottlerlab.com/
Recent publications from Shayn’s lab: https://www.peircecottlerlab.com/publications
Check out Dr. Shannon Barker's page: https://engineering.virginia.edu/faculty/shannon-barker
Read about combining synthetic biology, computational modeling, and machine learning to design and build tissues: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1010701
Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com
Executive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA
Senior Producer: Hannah Moore, Associate Director, UVA Coulter
Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com
Produced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research
Previous Episode
Dr. Tom Skalak on the Value of Research, Emerging Fields of Cognition and Human Performance, and the Art-Science Collaborations
Investment is critical for advancing promising biomedical research out of the lab and into the hospital. Dr. Tom Skalak has worked widely on innovation ecosystems with the White House, U.S. Congress, and Fortune 500 CEOs and C-suites seeking cultures to advance creative ideation and implementation of innovations. He urges VCs to invest locally with research universities and shares his perspective of some of the most exciting, emerging fields of research.
Love this podcast? Write to us with ideas, feedback, and guest recommendations at [email protected]
Tom Skalak joined the Joe and Clara Tsai Foundation in 2018 as Senior Advisor to Clara Wu Tsai and was previously the founding Executive Director of The Paul G. Allen Frontiers Group in Seattle, and Vice President for Research Emeritus at the University of Virginia. In these roles, Tom led creative synthesis of research and innovation programs spanning biosciences, environmental sustainability, physical sciences, engineering and technology, arts, design, entrepreneurship, and humanities. In this episode of Biomedical Frontiers, we dive into how small start-ups can grow and thrive in the competitive biomedical technology industry, innovative research in the discipline of protein design and the future applications, and the challenges in studying the emerging fields, human cognition and performance.
As Professor and Chair of Biomedical Engineering at UVAs, Tom’s original research included:
cardiovascular biomechanics, computational modeling, wound repair, and regenerative medicine, conducted with continuous NIH funding over 28 years. He is a past president of both the American Institute of Medical and Biological Engineering (AIMBE) and the Biomedical Engineering Society (BMES). He was the founder of the UVA-Coulter Foundation Translational Research Partnership and early-stage investment funds with corporate partners such as Johnson & Johnson and AstraZeneca.
Follow Dr. Tom Skalak on Social Media
LinkedIn: https://www.linkedin.com/in/tom-skalak-81000611b/
Learn more about the Human Performance Alliance: https://humanperformancealliance.org/
Faculty profile: https://engineering.virginia.edu/faculty/thomas-c-skalak
The Wu Tsai Institute at Yale: https://wti.yale.edu/
Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com
Executive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA
Senior Producer: Hannah Moore, Associate Director, UVA Coulter
Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com
Produced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research
Next Episode
Dr. Andrew DiMeo on Repeatable Innovation: Frameworks and Philosophy for Medical Device Design
What is innovation and why is it important to teach in an engineering program? Innovation has been defined as increasing value, which is increasing the benefits to cost ratio. Because innovation can be an ambiguous concept, it is important to develop a framework to guide the process. Since 2006, Dr. DiMeo has been coaching, consulting, and training processes of innovation, design thinking, and entrepreneurship for medical device innovation and healthcare impact.
Love this podcast? Write to us with ideas, feedback, and guest recommendations at [email protected]
Dr. Andrew DiMeo is a health innovator, biomedical engineer, design philosopher, and social entrepreneur. He began his career in New York, working on movies and TV shows, most notably The Sopranos. He has a BS in Physics and PhD in Biomedical Engineering and has spent most of his career teaching and practicing health innovation. In this episode of Biomedical Frontiers, we dive into Dr. DiMeo’s time teaching biomedical entrepreneurship at UNC and NC State, the teaching methodology and the philosophy for creating successful translational research classes, a new framework to help organizations innovate, and the future of STEM careers and education.
Dr. DiMeo has served as a Team Lead in NIH Programs, including RADx, ITAP, Blueprint MedTech, HIV Point of Care Testing, and C3i. He was previously a Professor of the Practice at UNC & NC State for 12 years where his students started multiple startups including 410 Medical, Contour Surgical, Augment Medical, Novocor Medical Systems, and MEDIC. He was co-founder of Gilero, founder of the NC Medical Device Trade Organization, and founder of CanvasGT, a SaaS startup acquired by Greenlight Guru. Today, you can find him mentoring the next generation of social entrepreneurs, working on his new venture, Hangar Dreys - a co-working concept in Raleigh, NC focused on addressing the loneliness epidemic.
Follow Dr. Andrew DiMeo on Social Media
LinkedIn: https://www.linkedin.com/in/ajdimeo/
IDEAL Biomedical Publication: https://medium.com/ideal-biomedical
Linktree: https://linktr.ee/andrewdimeo
Press Release about Springbok Analytics FDA approval:
Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com
Executive Producer: David Chen, Managing Director & Instructor of Engineering Design, UVA
Senior Producer: Hannah Moore, Associate Director, UVA Coulter
Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com
Produced on behalf of Wallace H. Coulter Center for Translational Research at University of Virginia https://engineering.virginia.edu/centers-institutes/coulter-center-translational-research
If you like this episode you’ll love
Episode Comments
Generate a badge
Get a badge for your website that links back to this episode
<a href="https://goodpods.com/podcasts/biomedical-frontiers-stories-with-innovators-in-healthcare-561263/dr-shayn-peirce-cottler-on-alzheimers-and-diabetes-how-disease-impacts-73644449"> <img src="https://storage.googleapis.com/goodpods-images-bucket/badges/generic-badge-1.svg" alt="listen to dr. shayn peirce-cottler on alzheimer's and diabetes, how disease impacts the smallest blood vessels on goodpods" style="width: 225px" /> </a>
Copy