Best Science Medicine Podcast - BS without the BS

In episode 529, Mike and James welcome Mike Kolber back to the podcast and we discuss all the best available around the use of tranexamic acid for acute adult trauma and acute GI bleed. It seems to have an effect in one of these. Tune in to find out the numbers. Show Notes 1) Tools...

In episode 535, Mike and James work through all the evidence and come up with the definitive (in our minds) answer as to whether or not statins cause muscle symptoms. They likely do in 1% of people, but if you have muscle symptoms when you are on a statin it is very unlikely it is because of the statin.

Show Notes
Tools for Practice
Wouldn’t Bet On it: What is the risk of muscle symptoms on statins?
https://gomainpro.ca/wp-content/uploads/tools-for-practice/1676944827_tfp334_statinmsk.pdf

Annual MEME talk Vancouver May 12/13, 2023
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CFPC Learn

In episode 536, Mike and James talk about 4 questions – Is any bacteriuria associated with altered mental state? – Does treating ASB improve/prevent clinical outcomes? – Does treating ASB improve altered mental state? – Do antibiotic reduction interventions for ASB affect patient outcomes? Tune in to find out the answers.

Show Notes
1) Tools for Practice
Asymptomatic bacteriuria in the elderly: Don’t drug the bugs?

2) Annual MEME talk Vancouver May 12/13, 2023
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3) CFPC Learn

In episode 573, James and Mike invite Jamie Falk back to the podcast to help us simplify all the evidence around using antipsychotics for difficult to treat depression. They do seem to “work”, but you really need to know the numbers around what “work” means. At the end of the podcast, you will!

Show notes
1) Tools for Practice
Overcoming Resistance: Antipsychotics for difficult to treat depression
2) MAKING EVIDENCE MATTER for EVERYONE CONFERENCE
Vancouver
May 24/25, 2024

In episode 524 – the first of a 2-part series about weight – James and Mike talk about why people wish to lose weight, the words we use to describe weight, the obesity paradox, all the cohort evidence around weight and mortality/cardiovascular disease/depression/osteoarthritis/fractures, and in a nice juxtaposition do it while eating rum and raisin ice cream – yes it is a thing.

Show Notes
1) The Nutrition Proposition
Book website

Amazon Link

2) In their own words: Topic analysis of the motivations and strategies of over 6,000 long‐term weight‐loss maintainers
Obesity (Silver Spring). 2022;30:751–7614)

3) Patients’ preferred terms for describing their excess weight: discussing obesity in clinical practice
Obesity (Silver Spring). 2012;20(1):147–50