February 2023: Adversity, Toxic Stress, and Racial Disparities in Children, and Evaluating the Evidence for Brain-Based Biotypes
02/01/23 • 39 min
This episode of AJP Audio features two articles from the February issue of AJP. First up, we have Nathaniel G. Harnett, Ph.D. (Harvard Medical School), discussing the impact of adversity and stress on racial disparities in childhood brain development among Black and White American children. Following that, Ziv Ben-Zion, Ph.D. (Yale University), discusses a non-exact replication study of a study published in AJP by Stevens et al. (previously featured on AJP Audio) looking at brain-based biotypes to guide treatment following trauma. And of course, we’ll check in with AJP Editor-in-Chief Dr. Ned Kalin about the rest of the February issue and how it all fits together.
- Harnett interview [01:05]
- How do less tangible factors like trauma, stress, and exposure to violence impact brain development? [03:07]
- What do you mean by toxic stress? [04:41]
- Why did you choose to focus on those regions of the brain? [06:01]
- Regional variability and privacy concerns [07:50]
- Limitations [09:11]
- Future research [10:59]
- Children and the limited control of their environment [12:10]
- Ben-Zion interview [13:39]
- Challenges of running a non-exact replication study [15:12]
- Limitations [18:35]
- Should researchers consider replication in study design? [21:26]
- Future research [24:24]
- Kalin interview [27:46]
- Dumornay et al. [28:08]
- Baldwin et al. [30:02]
- Cleary et al. [31:38]
- Ben-Zion et al. [34:15]
- Hien et al. [37:08]
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
Subscribe to the podcast here.
Listen to other podcasts produced by the American Psychiatric Association.
Browse articles online.
How authors may submit their work.
Follow the journals of APA Publishing on
This episode of AJP Audio features two articles from the February issue of AJP. First up, we have Nathaniel G. Harnett, Ph.D. (Harvard Medical School), discussing the impact of adversity and stress on racial disparities in childhood brain development among Black and White American children. Following that, Ziv Ben-Zion, Ph.D. (Yale University), discusses a non-exact replication study of a study published in AJP by Stevens et al. (previously featured on AJP Audio) looking at brain-based biotypes to guide treatment following trauma. And of course, we’ll check in with AJP Editor-in-Chief Dr. Ned Kalin about the rest of the February issue and how it all fits together.
- Harnett interview [01:05]
- How do less tangible factors like trauma, stress, and exposure to violence impact brain development? [03:07]
- What do you mean by toxic stress? [04:41]
- Why did you choose to focus on those regions of the brain? [06:01]
- Regional variability and privacy concerns [07:50]
- Limitations [09:11]
- Future research [10:59]
- Children and the limited control of their environment [12:10]
- Ben-Zion interview [13:39]
- Challenges of running a non-exact replication study [15:12]
- Limitations [18:35]
- Should researchers consider replication in study design? [21:26]
- Future research [24:24]
- Kalin interview [27:46]
- Dumornay et al. [28:08]
- Baldwin et al. [30:02]
- Cleary et al. [31:38]
- Ben-Zion et al. [34:15]
- Hien et al. [37:08]
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
Subscribe to the podcast here.
Listen to other podcasts produced by the American Psychiatric Association.
Browse articles online.
How authors may submit their work.
Follow the journals of APA Publishing on
Previous Episode
January 2023: Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial
Dr. Stefanie Russman Block (University of Michigan, Ann Arbor) discusses a trial looking at whether connectivity patterns in the brain can be used to predict treatment response in patients with obsessive-compulsive disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses childhood and neurodeveloment-related psychiatric disorders explored in the January issue.
- Russman Block interview [00:51]
- Exposure and response prevention versus stress management therapy [05:46]
- Investigating adolescents and adults [07:02]
- Clinical implications [08:29]
- Limitations [10:02]
- Further research [11:56]
- Kalin interview [12:57]
- Russman Block et al. [13:12]
- Webb et al. [14:57]
- Floris et al. [17:45]
- Shimelis et al. [21:27]
- Brikell et al. [26:04]
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
Subscribe to the podcast here.
Listen to other podcasts produced by the American Psychiatric Association.
Browse articles online.
How authors may submit their work.
Follow the journals of APA Publishing on Twitter.
E-mail us at [email protected]
Next Episode
March 2023: Adjunctive Cariprazine for the Treatment of Patients With Major Depressive Disorder
Dr. Gary S. Sachs (Harvard Medical School) joins us for the for the March episode of AJP Audio, discussing the results from a phase 3 study looking at the use of atypical antipsychotic cariprazine as an adjunctive treatment for major depression in conjunction with antidepressants. Afterwards, we’ll be joined once again by AJP Editor-in-Chief Dr. Ned Kalin to discuss the rest of the March issue.
- Sachs interview [00:47]
- Why is treating major depressive disorder in patients proven to be such a challenge for clinicians? [01:54]
- Why cariprazine in conjunction with antidepressants? [02:37]
- Atypical antipsychotics and antidepressants [03:22]
- Atypical antipsychotics and side effects [05:23]
- Limitations [07:09]
- Clinical implications for the treatment of major depressive disorder [08:29]
- What’s next for your research? [09:15]
- Kalin interview [10:09]
- Sachs et al. [10:25]
- Hasseris et al. [12:35]
- Visontay et al. [15:15]
- Dunlop et al. [17:10]
- Elbau et al. [19:56]
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
Subscribe to the podcast here.
Listen to other podcasts produced by the American Psychiatric Association.
Browse articles online.
How authors may submit their work.
Follow the journals of APA Publishing on Twitter.
E-mail us at [email protected]
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