搞乜咁科學 GMG Science

歡迎嚟到 搞乜咁科學 GMG Science 第33集!

今集嘅主題係《一個人生B與叻過ChatGPT Baby Making DIY & Human Outsmarting AI》🍼!Abellona講唔洗精子卵子都可以做到B? 🐣 Keith會講有咩你肯定叻過啲AI?!🤔

喂!好奇心,係時候醒喇 :)

Social Media:

科學一齊搞 Got Something for GMG - 有咩想同我哋講都可以係度share㗎: http://hello.gmgscience.com/

搞乜咁科學網頁: http://www.gmgscience.com

搞乜咁科學 IG: http://www.instagram.com/gmgscience

搞乜咁科學 YouTube: https://www.youtube.com/@gmgscience

Abellona IG: http://www.instagram.com/_doctor_u

Keith IG: http://www.instagram.com/keith.poonsir

Keith YouTube: http://www.youtube.com/@KeithPoonSir

後期製作 Ah Long IG: http://www.instagram.com/arlongphotog.hk

Show Notes and Links:

大部份今集有關嘅圖片會係我哋IG見到㗎: http://www.instagram.com/gmgscience

Abellona’s Part

體外人工受精 In vitro fertilisation - Wikipedia

改編自體外人工受精背後嘅故事嘅電影:Joy - Film

易入口d介紹體外人工製造卵子技術最新發展嘅文章:

Making Eggs Without Ovaries - Asimov Press

體外人工製造配子技術嘅科學雜誌總結:

Mitinori Saitou, Katsuhiko Hayashi ,Mammalian in vitro gametogenesis.Science374,eaaz6830(2021).DOI:10.1126/science.aaz6830

第一步:將幹細胞引導為初始生殖細胞,即係精子卵子嘅前驅細胞:

Hikabe, O., Hamazaki, N., Nagamatsu, G. et al. Reconstitution in vitro of the entire cycle of the mouse female germ line. Nature 539, 299–303 (2016). https://doi.org/10.1038/nature20104

第二步:使初始生殖細胞重寫佢DNA上面嘅tag (Epigenetic modification):

Murase, Y., Yokogawa, R., Yabuta, Y. et al. In vitro reconstitution of epigenetic reprogramming in the human germ line. Nature 631, 170–178 (2024). https://doi.org/10.1038/s41586-024-07526-6

第三步:有正確數量嘅染色體,分別係由兩個copy 變一個copy:

Aleksei Mikhalchenko et al. ,Induction of somatic cell haploidy by premature cell division. Sci. Adv. 10,eadk9001(2024).DOI:10.1126/sciadv.adk9001

同埋如果要將來自男性嘅細胞變成卵子,要由XY變成XX:

Murakami, K., Hamazaki, N., Hamada, N. et al. Generation of functional oocytes from male mice in vitro. Nature 615, 900–906 (2023). https://doi.org/10.1038/s41586-023-05834-x

第四部:培殖發展為成熟嘅精子/卵子

Takashi Yoshino et al. ,Generation of ovarian follicles from mouse pluripotent stem cells.Science373,eabe0237(2021).DOI:10.1126/science.abe0237

嘗試發展呢嘅技術嘅生物技術初創,例如:https://conception.bio

Keith’s Part

Ned Block 講 AI - Robinson Erhardt on YouTube

歡迎嚟到 搞乜咁科學 GMG Science 第24集!

今集係我哋 Not a Doctor 嘅 Nic 同 madformedic 上嚟做嘉賓~

我哋四個會每人分享一個自己覺得好有趣嘅故事或者知識,睇下邊個講嘅嘢係大家覺得最驚訝嘅?!

喂!好奇心,係時候醒喇 :)

Chapter
00:00 熱烈歡迎 Not a Doctor!!!
10:48 Abellona 的部份
24:25 @madformedic 的部份
35:28 Keith 的部份
52:44 Nic 的部份
01:24:28 Yeahhh!

Social Media:
科學一齊搞 Got Something for GMG - 有咩想同我哋講都可以係度share㗎: https://forms.gle/26RSEgW9NeeSMc4a7

搞乜咁科學網頁: www.gmgscience.com
搞乜咁科學 IG: www.instagram.com/gmgscience
搞乜咁科學 YouTube: https://www.youtube.com/@gmgscience
Abellona IG: www.instagram.com/_doctor_u
Keith IG: www.instagram.com/keith.poonsir
Keith YouTube: www.youtube.com/@KeithPoonSir
後期製作 Ah Long IG: www.instagram.com/arlongphotog.hk

嘉賓!
Not a Doctor: https://www.instagram.com/notadoctor.podcast
Mad for Medic: https://www.instagram.com/madformedic/

Show Notes and Links:

Abellona 的部分
Roberts RM, Green JA, Schulz LC. The evolution of the placenta. Reproduction. 2016 Nov;152(5):R179-89. doi: 10.1530/REP-16-0325. Epub 2016 Aug 2. PMID: 27486265; PMCID: PMC5033709.

@Mad for Medic的部分
【親子鑑定】滴血認親是甚麼一回事?其實所有血型都可以在水中混和,但卻不能用在醫療上?https://medicalinspire.com/posts/20755/【親子鑑定】滴血認親是甚麼一回事?其實所有血/

Keith的部分
Why are more boys born at the end of wars?
https://www.science20.com/david_spiegelhalter/why_are_more_boys_born_at_the_end_of_wars-154948

Nic@Not A Doctor的部分
Aphantasia Network
https://aphantasia.com

Extreme Imagination Online Exhibition - Centre for the Study of Perceptual Experience
https://www.gla.ac.uk/research/az/cspe/engagement/extreme-imagination/online-exhibition/

歡迎嚟到 搞乜咁科學 GMG Science 第21集!

今集嘅主題係聲音 Sound🔊!Keith會講點解你屋企部琴硬係唔啱音?🎹Abellona會講我地點樣用兩條飲管黎聽音樂?🎧

喂!好奇心,係時候醒喇 :)

Social Media:

科學一齊搞 Got Something for GMG - 有咩想同我哋講都可以係度share㗎: https://forms.gle/26RSEgW9NeeSMc4a7

搞乜咁科學網頁: www.gmgscience.com

搞乜咁科學 IG: www.instagram.com/gmgscience

搞乜咁科學 YouTube: https://www.youtube.com/@gmgscience

Abellona IG: www.instagram.com/_doctor_u

Keith IG: www.instagram.com/keith.poonsir

Keith YouTube: www.youtube.com/@KeithPoonSir

後期製作 Ah Long IG: www.instagram.com/arlongphotog.hk

Show Notes and Links:

大部份今集有關嘅圖片會係我哋IG見到㗎: www.instagram.com/gmgscience

Abellona's Part
Endometriosis UK

Vagina Museum

Outer Ear - Wikipedia

Georg von Békésy - The Nobel Prize

Ashmore J. (2018). The neuroscience of hearing or how to do a hard job with soft components. Brain and neuroscience advances, 2, 2398212818810687. https://doi.org/10.1177/2398212818810687

Fourier Transform - Wikipedia

Oppenheim, J. N., & Magnasco, M. O. (2013). Human time-frequency acuity beats the Fourier uncertainty principle. Physical review letters, 110(4), 044301. https://doi.org/10.1103/PhysRevLett.110.044301

Sound localization - Wikipedia

Keith’s Part

五度相生律 Pythagorean tuning - Wikipedia

純律 Just Intonation - Wikipedia

12 Equal Temperament 十二平均律 - Wikipedia

平均律鍵盤曲集 The Well-Tempered Clavier - Wikipedia

巴哈與十二平均律 - A Gertus History of Music

Pythagorean tuning vs 12 equal temperament - PTG HomeOffice

Chopin Étude Op. 10 No. 1 but it's in Just Intonation - ValkyRiver
Jacob Collier 話你知點解你部琴唔啱音! - George Collier

歡迎嚟到 搞乜咁科學 GMG Science 第20集!

今集嘅主題係『新發現 New in '23』 🪄!Keith會講點樣可以唔單調咁鋪地板?🧩 Abellona會講細菌抵抗病毒嘅武器而家可以用黎醫病?🩺

喂!好奇心,係時候醒喇 :)

Social Media:

科學一齊搞 Got Something for GMG - 有咩想同我哋講都可以係度share㗎: https://forms.gle/26RSEgW9NeeSMc4a7

搞乜咁科學網頁: www.gmgscience.com

搞乜咁科學 IG: www.instagram.com/gmgscience

搞乜咁科學 YouTube: https://www.youtube.com/@gmgscience

Abellona IG: www.instagram.com/_doctor_u

Keith IG: www.instagram.com/keith.poonsir

Keith YouTube: www.youtube.com/@KeithPoonSir

後期製作 Ah Long IG: www.instagram.com/arlongphotog.hk

Show Notes and Links:

大部份今集有關嘅圖片會係我哋IG見到㗎: www.instagram.com/gmgscience

Keith’s Part

Archimedean Tessellation 阿基米德密鋪平面 - Wikipedia
Plane vertex tiling - Wikipedia
Uniform tiling - Wikipedia
Zigzag path tiling 唔係長方形嘅長方形磚 - Pinterest
Uniform tiling using star polygon 星形啊!! - Wikipedia
Aperiodic tiling - 非週期性密鋪平面 - Wikipedia
Penrose tiling - misc
The Infinite Pattern That Never Repeats - Veritasium
Einstein Tile 愛因斯坦磚(?) - Wikipedia
How a Hobbyist Solved a 50-Year-Old Math Problem - Up and Atom

Abellona's Part

CRISPR - Wikipedia
Pioneers of revolutionary CRISPR gene editing win chemistry Nobel - Nature

Sickle Cell Disease - Wikipedia

Beta Thalassemia - Wikipedia

UK first to approve CRISPR treatment for diseases: what you need to know - Nature

FDA approves two gene therapies for sickle cell, bringing hope to thousands with the disease - CNN

Frangoul H, Altshuler D, Cappellini MD, et al. CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia. N Engl J Med. 2021;384(3):252-260. doi:10.1056/NEJMoa2031054

I received the new gene-editing drug for sickle-cell disease. It changed my life. - MIT Technology Review

Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ - BBC

歡迎嚟到 搞乜咁科學 GMG Science 第13集!

今集嘅主題知覺Sense🙈! Keith 會解釋1同9中間究竟係幾多 (提示: 唔係5) 🧮 Abellona 會講我地係點樣畀我地嘅視覺呃咗?👀

喂!好奇心,係時候醒喇 :)

Social Media:

科學一齊搞 Got Something for GMG - 有咩想同我哋講都可以係度share㗎: https://forms.gle/26RSEgW9NeeSMc4a7

搞乜咁科學網頁: www.gmgscience.com

搞乜咁科學 IG: www.instagram.com/gmgscience

搞乜咁科學 YouTube: https://www.youtube.com/channel/UCFj2cwjDASS2SyYsj3pkNSQ

Abellona IG: www.instagram.com/_doctor_u

Keith IG: www.instagram.com/keith.poonsir

Keith YouTube: https://youtube.com/c/KeithPoonSir

Show Notes and Links:

大部份今集有關嘅圖片會係我哋IG見到㗎: www.instagram.com/gmgscience

苜苜 @mukmuk.studio

ChatGPT - OpenAI

Keith’s part

對數 Logarithm - Wikipedia

心理物理學 Psychophysics - Wikipedia

韋伯-費希納定理 Weber–Fechner law - Wikipedia

分貝 Decibel - Wikipedia

Can Silence Actually Drive You Crazy? - Veritasium

小朋友或者偏遠地區的人會覺得 1 同 9 中間唔係 5 ? - MIT News

最小可覺差 Just Noticeable Difference - Wikipedia

Psychophysics of Prices Paradox - JSTOR

延伸閱讀:

1,2,3,4,5,6,7,8,9,10,11,12,13 ... - Vsauce

Abellona’s part

Akiyoshi Kitaoka - 佢嘅眼睛係咩顏色?

世紀爭議: 條裙咩色 The Dress - Wikipedia

Akiyoshi Kitaoka - 士多啤梨的顏色

顏色恆常性 - Wikipedia

傳籃球 1.0 版本 - Selective Attention Test

傳籃球 2.0 版本 - The Monkey Business Illusion

“Whodunnit?”

轉咗個人都察覺唔到? - The Door Study

Simons, D.J., Levin, D.T. (1998) Failure to detect changes to people during a real-world interaction. Psychonomic Bulletin & Review 5, 644–649.
Kennedy, K. D., Stephens, C. L., Williams, R. A., & Schutte, P. C. (2014) Automation and Inattentional Blindness in a Simulated Flight Task. Proceedings of the Human Factors and Ergonomics Society Annual Meeting 58 (1), 2058–2062.

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