Ep 43: Prevention and Management of Alloimmunization in Pregnancy

Practice Bulletins #181 and #192 - Reaffirmed in 2019
Five pearls:
1. Risk of alloimmunization is around 15% after 2nd delivery of an Rh positive fetus to an Rh negative mother; this risk is decreased dramatically with administration of postpartum RhoGam
2. RhoGam is never indicated if both mom and dad are Rh negative or in women who are already sensitized (indirect coombs screen)
3. The KB test can used to determine if excessive feto-maternal hemorrhage has occurred in order to guide RhoGam administration in less obvious cases such as abdominal trauma in pregnancy
4. Alloimmunization can present as mild to severe anemia; if concerning antibodies are found, serial titers and/or peak systolic velocity of the middle cerebral artery ma be indicated
5. "Kell kills"
Show Notes
SIGN UP FOR LOUISVILLE BREECH WORKSHOP!
Wine pairing: 2017 Pinot Noir from Longford Estate Wines
Theme music by Evan Handyside
Logo design by JD Dotson ([email protected])